Cell Biology & Genetics I

Paper Code: 
ZOL 102
Credits: 
03
Contact Hours: 
45.00
Max. Marks: 
100.00
11.00
Unit I: 
  • Diversity of Cell Size & shape
  • Cell theory
  • Structure of Prokaryotic & Eukaryotic cells
  • Magnification , resolving power
  • Principles of microscope and application:
Light Microscope
 
 Electron Microscopy (SEM & TEM)
 

           

 
12.00
Unit II: 

Cell organelles, their structure, composition & function

  • Endoplasmic reticulum
  • Golgi complex
  • Ribosome : structure & functions
  • Lysosomes: Function & intracellular digestion
  • Mitochondria: Organization & function, and Oxidative phosphorylation
  • Peroxisomes
  • Centrioles & Microtubules: cilia & flagella
 

 

8.00
Unit III: 
  • Active and Passive transport across membranes
  • Pinocytosis, Phagocytosis
  • Endocytosis, Exocytosis
  • Nucleus structure:  Structure & function of nuclear envelope, nuclear matrix and nucleolus
  •  Cell cycle( S, G1,G2,M phase)
  • Mitosis: Phases & process of mitosis,
  • Meiosis: Phases & Process of meiosis
 
8.00
Unit IV: 
  • Mendelian inheritance patterns & laws of heredity
  • Co and incomplete dominance
  • Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
  • Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
  • Gene expression- Lethal genes, Pleiotropic genes
  • Multiple genes- Seed coat in wheat, skin colour in human
 
6.00
Unit V: 
  • Linkage & linkage maps
  • Crossing over- Mechanism, theories, Cytological detection & significance
  • Cytoplasmic inheritance
     
Essential Readings: 
  • Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
  • Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
  • Essentials cell Biology II Ed., Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings.
  • Cell and Molecular Biology; Phillip Sheeler   Donald E. Bianchi; John Wiley and Sons.
  • The Cell: A Molecular Approach. Cooper, G. Houseman G.R. Sinaeur Assoc, New York.
  • Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
  • Genetics; Strickberger; Macmillan, Prentice Hall of India.
  • Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
  • Primose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, Willey- Blacwell.
  • Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
  • A Textbook of Genetics; Rastogi, V.B.; Ramnath & Kedarnath.
  • Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings  
  • Cell and Molecular Biology; Phillip Sheeler,   Donald E. Bianchi; John Wiley and Sons.

 

 

 

Academic Year: