Cell Biology & Genetics I

Paper Code:

ZOL 102

Credits:

03

Contact Hours:

45.00

Max. Marks:

100.00

11.00

Unit I:

Diversity of Cell Size & shape
Cell theory
Structure of Prokaryotic & Eukaryotic cells
Magnification , resolving power
Principles of microscope and application:

Light Microscope

Electron Microscopy (SEM & TEM)

12.00

Unit II:

Cell organelles, their structure, composition & function

Endoplasmic reticulum
Golgi complex
Ribosome : structure & functions
Lysosomes: Function & intracellular digestion
Mitochondria: Organization & function, and Oxidative phosphorylation
Peroxisomes
Centrioles & Microtubules: cilia & flagella

8.00

Unit III:

Active and Passive transport across membranes
Pinocytosis, Phagocytosis
Endocytosis, Exocytosis
Nucleus structure: Structure & function of nuclear envelope, nuclear matrix and nucleolus
Cell cycle( S, G1,G2,M phase)
Mitosis: Phases & process of mitosis,
Meiosis: Phases & Process of meiosis

8.00

Unit IV:

Mendelian inheritance patterns & laws of heredity
Co and incomplete dominance
Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
Gene expression- Lethal genes, Pleiotropic genes
Multiple genes- Seed coat in wheat, skin colour in human

6.00

Unit V:

Linkage & linkage maps
Crossing over- Mechanism, theories, Cytological detection & significance
Cytoplasmic inheritance

Essential Readings:

Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
Essentials cell Biology II Ed., Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings.
Cell and Molecular Biology; Phillip Sheeler Donald E. Bianchi; John Wiley and Sons.
The Cell: A Molecular Approach. Cooper, G. Houseman G.R. Sinaeur Assoc, New York.

Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
Genetics; Strickberger; Macmillan, Prentice Hall of India.
Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
Primose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, Willey- Blacwell.
Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
A Textbook of Genetics; Rastogi, V.B.; Ramnath & Kedarnath.
Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings
Cell and Molecular Biology; Phillip Sheeler, Donald E. Bianchi; John Wiley and Sons.

Academic Year: