Biochemistry

Paper Code: 
ZOL 124
10.00
Unit I: 

Biocatalysis

  • Classification and nomenclature of enzymes
  • Mechanism of enzyme action
  • Enzyme kinetics
  • Inhibition of enzyme
  • Isoenzymes and co-enzymes

Energy consideration

  • Biological oxidation and reduction
  • Fundamental reactions of biological oxidation
  • Redox potential and electron transfer system enzymes
     
14.00
Unit II: 

Carbohydrates

  • Definition , general properties, classification and configuration of carbohydrates

Metabolism

  • Catabolism of glycogen and glucose, details of glycolysis , Krebs cycle and Cori’s cycle
  • Phosphogluconate pathways(pentose phosphate pathway)

Synthesis of glycogen; glycogenesis and gluconeogenesis
Inborn errors of metabolism
 

12.00
Unit III: 

Lipids

  • Definition, general properties and classification
  • Structure and importance of -:
  1. Simple lipids- fats and wax
  2. Compound lipids- phospholipids, glycolipids, aminolipids and sulpholipids
  3. Steroids- cholesterol, bile acids, steroid hormones
  4. Lipoproteins

Lipid Metabolism- Beta oxidation and Lipogenesis.
Inborn errors of metabolism
 

14.00
Unit IV: 

General properties and classification of proteins

  • Amino acid structure and classification
  • Structure of protein-Primary, Secondary, Tertiary and Quartenary
  • Ramachandran plots
  • Globular and fibrous protein- motif in globular proteins
  • Protein sequencing
     
10.00
Unit V: 

Protein metabolism

  • Amino acid degradation:Deamination reaction- Oxidative and non oxidative deamination reaction, transamination and transdeamination, Decarboxylation, Ornithine cycle of urea formation , Fate of carbon skeleton of amino acids(Metabolism of individual amino acid excluded)

Inborn errors of metabolism

Essential Readings: 
  1. Biochemistry; Voet &Voet ; John Wiley & Sons
  2. Outlines of Biochemistry; Conn, E.E. and Stumpf  P.K. ; John Wiley, New   York.
  3. Principles of Biochemistry; Smith; Mc Graw hill, New York.
  4. Biochemistry; Stryer, L; Freeman Publications.
  5. Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R.:  Orient Longman, Madras
  6. Biochemistry, D.Voet and J.G.Voet, John Wiley & Sons, (2nd Edition), 1995.
  7. Principles of Biochemistry, Lehninger ,Nelson and Cox, (3rd Edition), 1999.
  8. Principles and Techniques in Biochemistry and Molecular Biology, Edited by Keith Wilson and John Walker, Cambridge University Press, (6th Edition), 2007.
  9. Biochemistry and Molecular Biology by W.H. Elliot and Daphne C. Elliot, Oxford University Press, (3rd Edition), 2005.
  10. Biochemistry, J. David Rawn, Panima Publishing Corporation, 1st Indian Reprint, 2004.
  11. Physical Biochemistry, D Friefelder, W.H. Freeman & Company, 17th Reprint, 1999.
  12. Understanding Chemistry, CNR Rao, University Press, Hyderabad 1999.
  13. A Biologist's Guide to Principles and Techniques of Practical Biochemistry, K.Wilson & KH Goulding, ELBS Edition 1986

      14.   Essentials of Molecular Biology, David Friefelder, Jones and Barllett Publications,7th Reprint, 2001.

      15.    Instant Notes- Biochemistry (1st Indian Edition), B.D. Hames and N.M. Hooper, Viva Books Pvt, Ltd.2001.                            

Academic Year: 
2018-2019
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