Immunology

Paper Code: 
ZOL-512
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 
Course objectives: 
This course will enable the students to - 
1. Appraise Primary and Secondary organs of the Immune system. 
2. Analyze antibody-antigen interaction, autoimmune diseases, the concept of antigen, antigenic  determinants, hapten, factors affecting antigenicity 
3. Critique the structure, types, and functions of Immunoglobulin 
4. Relate the functioning of CD4 and CD8 T cells and B cells in immune responses. 
5. Acquainted with how the immune system distinguishes self from non-self. 
 
Course Outcomes (COs):  
 

Course 

Learning outcomes 

(at course level)

Learning and  teaching strategies

Assessment  Strategies 

Paper  

Code

Paper Title

ZOL 512 

Immunology 

Students will  

CO 86: Distinguish primary and  secondary organs of the Immune  system. 

CO 87: Examine antibody-antigen  interaction, autoimmune diseases, the  concept of antigen, antigenic  determinants, hapten, factors affecting  antigenicity 

CO 88: Investigate the structure, types  and functions of Immunoglobulin,  CO 89: Scrutinize the major cellular  and tissue components which comprise  the innate and adaptive immune  system. Understand how immune responses by CD4 and CD8 T cells,  and B cells are initiated and regulated. 

The approach in  teaching: 

Interactive Lectures,  Discussion, Tutorials,  Reading assignments,  Demonstration,  

PowerPoint  

presentations,  

Explanation by videos 

Learning activities for  the students: 

Self learning  assignments, Effective  questions, Simulation,  Seminar presentation,  Giving tasks, Field  practical

Class test  

Semester end  examinations, Quiz,  

Assignments,  Presentation 

Surprise test 

Open book test
 
7.00
Unit I: 
UNIT I:
● Immunology 
● Definition 
● Types of immunity: innate and acquired 
● Antigen: Antigenicity of molecules, Immunogenicity and its properties, haptens, adjuvants
 
10.00
Unit II: 
UNIT II:
● Antibody 
● Definition. 
● Structure , effector function 
● (IgG. IgM. IgD. IgA and IgE) 
● Properties and function of each class of immunoglobulin. 
● Isotype, Allotype, Ideotype 
● Antigen-antibody reactions 
● Precipitation reaction 
● Agglutination reaction 
10.00
Unit III: 
UNIT III:
● Cells and organs of Immunity 
● Primary and Secondary lymphoid organs 
● Dendritic cells 
● Macrophages. 
● Lymphocytes (B- and T- types). T.- Helper cells. T-killer cells, plasma cells and memory cells 
 
12.00
Unit IV: 
UNIT IV:
● MHC genes and gene products. 
● Cytokines: Types, Properties and Function.
● Complement and its action 
 
8.00
Unit V: 
UNIT V:
● Autoimmunity : Hashimoto thyroiditis, Myasthenia gravis, Rheumatoid arthritis, Lupus 
● Immunodeficiency: AIDS- causes, symptoms, treatment, mode of infection, HIV lifecycle ● Hypersensitivity- Type I to IV 
 
Essential Readings: 
● Roitt’s essential Immunology, P. Delves, et al., 11th ed., Blackwell Publishing, 2006
● Kindt, T. J., Goldsby, R.A., Osborne, B. A. and Kuby, J (2006). Immunology, VI Edition.  W.H. Freeman and Company. 
 
References: 
SUGGESTED READINGS:
● David, M., Jonathan, B., David, R. B. and Ivan R. (2006). Immunology,VII Edition, Mosby,  Elsevier Publication. 
● Abbas, K. Abul and Lechtman H. Andrew (2017) Cellular and Molecular Immunology. V  Edition. Elsevier; 9th edition 
 
e-RESOURCES: 
 
e-JOURNAL: 
● Immunology- Wiley online Library- ISSN 1365-2567
● Scandinavian Journal of Immunology-Online ISSN: 1365-3083
 
 
Academic Year: 
2022-2023
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