Genetics & Biostatistics

Paper Code: 
ZOL 214
Credits: 
3
Contact Hours: 
3.00
Max. Marks: 
100.00
9.00

Mendelian inheritance patterns & laws of heredity

Co and incomplete dominance

Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)

Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh

Gene expression- Lethal genes, Pleiotropic genes

Multiple genes- Seed coat in wheat, skin colour in human
 

 

7.00

Linkage & linkage maps

Crossing over- Mechanism, theories, Cytological detection & significance

Cytoplasmic inheritance

Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis

Eugenics & Euthenics
 

 

10.00

Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory,

Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes

Mutations- Chromosomal aberrations, Gene mutations
 

 

10.00

Introduction, scope and application of Biostatistics

Frequency distribution

Graphical presentation of data (bar diagram, frequency polygon, histogram, pie chart)
 

 

9.00

Mean. mode, median and their significance

Standard deviation ,variance and coefficient of variance

Tests of significance- t-test(1 population & 2 population test), Chi-square( independence of attributes)
 
Essential Readings: 
  • Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
  • Genetics; Strickberger; Macmillan, Prentice Hall of India.
  • Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
  • Primose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, Willey- Blacwell.
  • Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
  • A Textbook of Genetics; Rastogi, V.B.; Ramnath & Kedarnath.
  • Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings  
  • Cell and Molecular Biology; Phillip Sheeler,   Donald E. Bianchi; John Wiley and Sons.
  • Biostatistics; Gupta, S.P.;Sultan Chand &Co.
  • Bencroft, H. Introduction to Biostatistics Harper and Row. New York, 1957.
  • Bailey, N.T.J. Statistical method in Biology Low Priced Text Book English Language Society, London, 1959.
  • Bishop O.N. Statistics for biology, Prentice Hall Press
  • Mahajan B.K., Methods in Biostatistics, Jaypee.

 

 

 

 

Academic Year: 
2018-2019
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