Cell Biology

Paper Code: 
ZOL 122
9.00
Unit I: 

Cell Theory
Structure of prokaryotic and eukaryotic cells.
Bio-membranes

  • Molecular composition and function
  • Transport across cell membrane: diffusion, active transport and pumps.
  • Co-transport by symporters or antiporters
     
9.00
Unit II: 

Cytoskeleton

  • Microfilaments, intermediate  filaments and microtubules-  structure and dynamics
  • Cell movements-Intracellular transport, role of kinesin and dynein
15.00
Unit III: 

Cell –Cell Signaling and Cell Interaction

  • Introduction
  • Cell surface receptors
  • Second messenger system
  • MDP kinase pathways

Cell junctions
Cell adhesion
 

15.00
Unit IV: 

Cell cycle

  • Cyclin and cyclin dependent kinases
  • Regulation of CDK – cyclin activity

Chromosomes, Chromatin,

  • Chromosome sequence and diversity
  • Nucleosomes
     
12.00
Unit V: 

Intracellular protein traffic

  • Protein synthesis
  • Uptake into ER
  • Membrane proteins, Golgi sorting, Post translational modifications

Apoptosis

  • Definition ,mechanism and significance
Essential Readings: 
  1. Cell and Molecular Biology; De Robertis and De Robertis; Saunders College
  2. Cell Biology;  Powar, C.B.; Himalaya Publications.
  3. Molecular Biology of the gene; Watson J.D; Benzamin/ Cummings
  4. Molecular Biology of the Gene. I.D Watson, N.H. Hopkins, J.W. Roberts, J.A. Steiz and AM Weiner The Benjamin/Cummings Pub. Co., Inc., California.
  5. Molecular Cell Biology, J. Darnell H.Lodish and D. Baltimore Scientific American Books, Inc., USA.
  6. Molecular Biology of the cell. B.Alberts, D.D.Bray, J.Lewis, M.Rafif, K. Roberts and J.D.Watson. Garland Publishing inc., New York.
  7. Gene IV, Benjamin Lewin. Oxford University Press, UK.
  8. Molecular Biology and Biotechnology. A comprehensive desk reference, R.A.Meyers (Ed.), VCH Publishers, Inc., New York.
  9. Molecular Cloning: A Laboratory Manual, J.Sambrook, E.F.Fristsch and T. Maniatis, Cold Spring Harbor Laboratory Press, New York.
  10. Introduction to Practical Molecular Biology, P.D.Dabre, John Wiley& Sons Ltd. New York.
  11. Molecular Biology Lab Fax, T.A.Brown (Ed.), Bios Scientific Publishers Ltd., Oxford.
     
Academic Year: 
2018-2019
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