Cell Biology& Genetics I

Paper Code: 
ZOL-102
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

Course Objectives:

This course will enable the students to

1. Develop an understanding of the structure and functions of basic components of prokaryotic architecture and eukaryotic cells and their organelles

2. To provide an overview of cell theory, role of membrane in transport of biomolecules across the cell and how these cellular components are used to generate and utilize energy in cells.

3. Learn about the process of cell division in both somatic and germ cell

4. Develop understanding of mendelian inheritance patterns & laws of heredity, Interactions of Genes and their expressions, process of crossing over and linkage in genes etc.

Course Outcomes (COs): 

 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

ZOL-102

Cell Biology & Genetics I

The students will be able to –

CO5: Understand the structures and purposes of basic components of prokaryotic and eukaryotic cells, especiallymacromolecules, membranes, and organelles.

CO6: Describe the function and        composition of the plasma membrane.

CO7: Understand the importance of the nucleus and its components and process of cell division

CO8: Describe how the endoplasmic reticulum and golgi apparatus interact with one another and know with which other organelles they are associated.

CO9: Perceive detailed knowledge about the patterns of Mendelian inheritance and interactions of Genes and their expressions.

CO10: Describe role of crossing over and linkage in heredity and cytoplasmic inheritance.

Approach in teaching:

Class Lectures, Discussion, Tutorials, Reading assignments, Demonstration

Learning activities for the students:

Self-learning assignments, Effective questions, Question preparation, Seminar presentation, Giving tasks.

Regular Class testSemesterendexaminations

Quiz

Solving problems in tutorials

Assignments

Presentation

Individual and group projects

 

11.00
Unit I: 
UNIT I
Diversity of Cell Size & shape 
Cell theory
Structure of Prokaryotic & Eukaryotic cells
Cell membrane structure and function
Active and Passive transport across membranes
Pinocytosis, Phagocytosis
Endocytosis, Exocytosis
12.00
Unit II: 
UNIT II
Cell organelles, their structure, composition & function
Endoplasmic reticulum
Golgi complex
Ribosome : structure & functions
Lysosomes: Function & intracellular digestion
Mitochondria: Organization &function, and Oxidative phosphorylation 
Peroxisomes 
Centrioles & Microtubules: cilia & flagella
 
8.00
Unit III: 
UNIT III
Nucleus structure:  Structure & function of nuclear envelope, nuclear matrix and nucleolus
Cell cycle( S, G1,G2,M phase)
Mitosis: Phases & process of mitosis
Meiosis: Phases & Process of meiosis
 

 

8.00
Concepts of Genetics
Mendelian inheritance patterns & laws of heredity
Co and incomplete dominance
Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
Gene expression- Lethal genes, Pleiotropic genes
Multiple genes- skin colour in human
6.00
Unit V: 
UNIT V
Linkage&construction of linkage maps 
Crossing over- Mechanism, theories, Cytological detection & significance
Cytoplasmic inheritance
 
Essential Readings: 
Cell Biology by C.B. Powar; Himalaya Publishing House.
Cell and Molecular Biology; Phillip Sheeler   Donald E. Bianchi; John Wiley and Sons. 
The Cell: A Molecular Approach. Cooper, G. Houseman G.R. SinaeurAssoc, New York.
 

 

References: 
Cell and Molecular Biology; De Robertis and De Robertis; Saunders College. 
Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
Essentials cell Biology II Ed., Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishing.
Genetics; Winchester, A.M; Oxford and IBH Publishing Co. 

 

Academic Year: 
2020-2021
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