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Cell Biology
Paper Code:
ZOL-122
Credits:
4
Contact Hours:
60.00
Max. Marks:
100.00
9.00
Cell Theory
Structure of prokaryotic and eukaryotic cells.
Bio-membranes
- Molecular composition and function
- Transport across cell membrane: diffusion, active transport and pumps.
- Co-transport by symporters or antiporters
9.00
Cytoskeleton
- Microfilaments, intermediate filaments and microtubules- structure and dynamics
- Cell movements-Intracellular transport, role of kinesin and dynein
15.00
Cell –Cell Signaling and Cell Interaction
- Introduction
- Cell surface receptors
- Second messenger system
- MDP kinase pathways
Cell junctions
Cell adhesion
15.00
Cell cycle
- Cyclin and cyclin dependent kinases
- Regulation of CDK – cyclin activity
Chromosomes, Chromatin, and the Nucleosomes
· Chromosome sequence and diversity
Nucleosomes
12.00
Intracellular protein traffic
- Protein synthesis
- Uptake into ER
- Membrane proteins, Golgi sorting, Post translational modifications
Apoptosis
Definition ,mechanism and significance
Essential Readings:
- Cell and Molecular Biology; De Robertis and De Robertis; Saunders College
- Cell Biology; Powar, C.B.; Himalaya Publications.
- Molecular Biology of the gene; Watson J.D; Benzamin/ Cummings
- Molecular Biology of the Gene. I.D Watson, N.H. Hopkins, J.W. Roberts, J.A. Steiz and AM Weiner The Benjamin/Cummings Pub. Co., Inc., California.
- Molecular Cell Biology, J. Darnell H.Lodish and D. Baltimore Scientific American Books, Inc., USA.
- Molecular Biology of the cell. B.Alberts, D.D.Bray, J.Lewis, M.Rafif, K. Roberts and J.D.Watson. Garland Publishing inc., New York.
- Gene IV, Benjamin Lewin. Oxford University Press, UK.
- Molecular Biology and Biotechnology. A comprehensive desk reference, R.A.Meyers (Ed.), VCH Publishers, Inc., New York.
- Molecular Cloning: A Laboratory Manual, J.Sambrook, E.F.Fristsch and T. Maniatis, Cold Spring Harbor Laboratory Press, New York.
- Introduction to Practical Molecular Biology, P.D.Dabre, John Wiley& Sons Ltd. New York.
- Molecular Biology Lab Fax, T.A.Brown (Ed.), Bios Scientific Publishers Ltd., Oxford.
Academic Year:
