Cell Biolog

Paper Code: 
ZOL-122
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
9.00

Cell Theory

Structure of prokaryotic and eukaryotic cells.

Bio-membranes

  • Molecular composition and function
  • Transport across cell membrane: diffusion, active transport and pumps.
  • Co-transport by symporters or antiporters
9.00

Cytoskeleton

·     Microfilaments, intermediate  filaments and microtubules-  structure and dynamics

·     Cell movements-Intracellular transport, role of kinesin and dynein

15.00

Cell –Cell Signaling and Cell Interaction

  • Introduction
  • Cell surface receptors
  • Second messenger system
  • MDP kinase pathways

 

Cell junctions

Cell adhesion

15.00

Cell cycle

  • Cyclin and cyclin dependent kinases
  • Regulation of CDK – cyclin activity

Chromosomes, Chromatin, and the Nucleosomes

  • Chromosome sequence and diversity

Nucleosomes

12.00

Intracellular protein traffic

  • Protein synthesis
  • Uptake into ER
  • Membrane proteins, Golgi sorting, Post translational modifications

Apoptosis

Definition ,mechanism and significance

Essential Readings: 
  • Cell and Molecular Biology; De Robertis and De Robertis; Saunders College
  • Cell Biology;  Powar, C.B.; Himalaya Publications.
  • Molecular Biology of the gene; Watson J.D; Benzamin/ Cummings
  • Molecular Biology of the Gene. I.D Watson, N.H. Hopkins, J.W. Roberts, J.A. Steiz and AM Weiner The Benjamin/Cummings Pub. Co., Inc., California.
  • Molecular Cell Biology, J. Darnell H.Lodish and D. Baltimore Scientific American Books, Inc., USA.
  • Molecular Biology of the cell. B.Alberts, D.D.Bray, J.Lewis, M.Rafif, K. Roberts and J.D.Watson. Garland Publishing inc., New York.
  • Gene IV, Benjamin Lewin. Oxford University Press, UK.
  • Molecular Biology and Biotechnology. A comprehensive desk reference, R.A.Meyers (Ed.), VCH Publishers, Inc., New York.
  • Molecular Cloning: A Laboratory Manual, J.Sambrook, E.F.Fristsch and T. Maniatis, Cold Spring Harbor Laboratory Press, New York.
  • Introduction to Practical Molecular Biology, P.D.Dabre, John Wiley& Sons Ltd. New York.
  • Molecular Biology Lab Fax, T.A.Brown (Ed.), Bios Scientific Publishers Ltd., Oxford.

 

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