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IIS University

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It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Admissions

It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Placements

Excellent education not only imparts knowledge, but also paves the way for a promising and successful career. The Placement Cell at The IIS University has numerous success stories to narrate in this regard...

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Life@IIS Univ

Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with vibrant events and memorable occasions to cherish for a lifetime.

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Academics

Taking the age-old tradition of enlightenment through education forward, The IIS University - in its continuous pursuit of excellence - firmly believes that an institution’s academic profile determines its worth and value. Therefore, on offer are a wide variety of both conventional and contemporary programmes of study.

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Research

To stimulate curiosity and cater to the global needs of a dynamic education, The IIS University - since inception - has been promoting and encouraging research-based experiential learning among all its students.

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About Us

The IIS University, with its perfect amalgamation of innovation, inspiration and synergy, aims to be a model institution for students across disciplines and programmes.

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IIS Univ
  • Admissions

    It is a University which is committed to excellence and overall development of the student...

  • Placements

    Excellent education not only imparts knowledge, but also paves the way for...

  • Life@IIS Univ

    Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with...

  • Academics

    Taking the age-old tradition of enlightenment through education forward,...

  • Research

    To stimulate curiosity and cater to the global needs of a dynamic education,...

  • About Us

    The IIS University, with its perfect amalgamation of innovation, inspiration...

IIS (Deemed to be University)

Gurukul Marg, SFS, Mansarovar, Jaipur 302020, (Raj.) India

Phone:- +91-141-2400160-61, 2397906-07,

Fax: 2395494,2781158, Toll Free No.: 1800 180 7750

Cancer Biology | Zoology

Cancer Biology

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Paper Code: 
LSC 144 J
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
12.00
Unit I: 
UNIT I
BIOLOGY OF CANCER
Cell cycle and cancer, the nature and types of cancer
Cellular oncogenes and Tumor suppressor genes: DNA viruses, retroviruses, proto oncogenes, tumor suppressor genes, pRb and control of the cell cycle clock, p53 and apoptosis
Tumor immunology: immune mediate
12.00
Unit II: 
UNIT II
TOXICITY AT CELLULAR LEVEL AND ENZYMOLOGY INVOLVED
Mechanism of toxicity: toxicity of O2, xenobiotics, mutagens and carcinogens
Multistage carcinogenesis: chemical carcinogens-genotoxic, nongenotoxic and inorganic carcinogens
Biotransformation of xenobiotics through liver detoxification (Phase I and II)
Mechanism of repair (molecular and cellular), toxicity resulting from inappropriate repair
12.00
Unit III: 
UNIT III
PRINCIPLES OF CANCER TREATMENT
Natural history of cancer therapy, ethical and philosophical issues
Treatment available: surgery, radiation, chemotherapy, biological therapy, gene therapy
12.00
Unit IV: 
UNIT IV
PRINCIPLES OF CANCER SCREENING AND CHEMOPREVENTION OF CANCER
Screening of cancer and the biases of screening, screening of specific cancers
Chemoprevention: Chemopreventive agents from natural products, preclinical animal model selection, phytopharmaceuticals in cancer chemoprevention
12.00
Unit V: 
UNIT V
TEST SYSTEMS/ASSAYS USED IN CANCER
Carcinogenicity assessment: short term tests for mutagenicity, chronic testing for carcinogenicity and transgenic animals in carcinogenicity assessment
Assays for detecting genetic alterations: DNA damage and repair assays, genetic alteration in mammals, mammalian cytogenetic assays, germ cell mutagenesis
New approaches to genetic toxicology
Essential Readings: 
Casarett & Doull’s (7th ed ) Toxicology: The basic Science of Poisons, Curtis D. Klassen
• Haskell: Caner Treatment (4th Ed), W.B Saunders Company, Mc. Graw Hill.
• Pecckham, Pinedo and Veronesi: Oxford Textbook of Oncology,Vol:1 and 2.
• Chemoprevention of Cancer and DNA Damage by Dietary Factors: Edited by Siegfried Knasmüller, David M. DeMarini, Ian Johnson, and Clarissa Gerhäuser. WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Academic Year: 
2019-2020
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