Course Objectives:
This course will enable the students to
1. To provide students with a basic understanding of chemical nature of biological macromolecules, their three-dimensional construction, and the principles of molecular recognition
2. Learn about different types of chemical bonds in biomolecules and their classification.
3. To understand metabolism of dietary and endogenous carbohydrate, lipid, and protein; and inborn errors related to metabolism.
4. Develop an understanding of sources and functions of vitamins and their deficiency diseases.
Course Outcomes (COs):
Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL302 |
BIOCHEMISTRY |
The students will be able to – CO30: Describe properties of water, acid base nature, different types of chemical bonds in biomolecules. CO31: Learn and describe structure and classification of carbohydrate and lipids CO32: Demonstrate knowledge and understanding of the principles that govern the structures of macromolecules and their participation in molecular recognition CO33: Understand the principles of bioenergetics and enzyme catalysis. CO34: Know about in born errors of carbohydrate metabolism, lipid metabolism and vitamins deficiency diseases. |
Approach in teaching: Interactive class Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical
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Class test Semester end examinations Quiz Assignments Presentation Individual and group projects |
Carbohydrates
Classification, Properties of Monosacharides,
Metabolism- Glycolysis, Krebs cycle, Gluconeogenesis, Hexose Monophosphate Pathway& Oxidative phosphorylation,Interconversion of glycogen and glucose in liver
Lipids
Classification, Metabolism- Biosynthesis of Palmitic acid, Beta-oxidative pathway of fatty acids.
Proteins-
Primary ,Secondary, tertiary and quaternary structure of Proteins,Amino acids-Classification andStructure;Catabolism of amino acids- Oxidative Deamination, Transamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)
pH and Buffers
Bioenergetics(Thermodynamic laws and ATP);
Vitamins
Fat soluble & Water soluble vitamins(Source, Function and Deficiency)
Enzymes: Classification
Mechanism of Enzyme action, activation energy
Kinetics (Michaelis-Menten Equation)
Factors affecting enzyme action
Enzyme Inhibition