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It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Admissions

It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Placements

Excellent education not only imparts knowledge, but also paves the way for a promising and successful career. The Placement Cell at The IIS University has numerous success stories to narrate in this regard...

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Life@IIS Univ

Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with vibrant events and memorable occasions to cherish for a lifetime.

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Academics

Taking the age-old tradition of enlightenment through education forward, The IIS University - in its continuous pursuit of excellence - firmly believes that an institution’s academic profile determines its worth and value. Therefore, on offer are a wide variety of both conventional and contemporary programmes of study.

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Research

To stimulate curiosity and cater to the global needs of a dynamic education, The IIS University - since inception - has been promoting and encouraging research-based experiential learning among all its students.

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About Us

The IIS University, with its perfect amalgamation of innovation, inspiration and synergy, aims to be a model institution for students across disciplines and programmes.

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IIS Univ
  • Admissions

    It is a University which is committed to excellence and overall development of the student...

  • Placements

    Excellent education not only imparts knowledge, but also paves the way for...

  • Life@IIS Univ

    Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with...

  • Academics

    Taking the age-old tradition of enlightenment through education forward,...

  • Research

    To stimulate curiosity and cater to the global needs of a dynamic education,...

  • About Us

    The IIS University, with its perfect amalgamation of innovation, inspiration...

IIS (Deemed to be University)

Gurukul Marg, SFS, Mansarovar, Jaipur 302020, (Raj.) India

Phone:- +91-141-2400160-61, 2397906-07,

Fax: 2395494,2781158, Toll Free No.: 1800 180 7750

SPECIAL PAPER: HUMAN GENETICS- II | Zoology

SPECIAL PAPER: HUMAN GENETICS- II

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Paper Code: 
ZOL 423 D
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
12.00
Unit I: 
UNIT I

 

Genetic variation – History, Categories of mutations,  chromosome and gene mutations, Extrachromosomal mutations, Mutator genes, Mobile genetic elements, Induced mutations, Physical and chemical mutagenes,  Molecular basis of spontaneous and induced mutations, DNA repair mechanisms, Reversion, Transposon mutagenesis, In vitro mutagenesis, Environmental mutagenesis
Chromosome rearrangements and Cancer.

Chromosomal aberration :

Numerical : Aneuploidy, Polyploidy  

Structural : Translocation, Duplication, Inversion, Ring Chromosome and Deletion  

Others : Mosaic, Chimera [Individual with two cell lines]

12.00
Unit II: 
UNIT II

 

Immunogenetics - 

Genetics of normal immune system. Inherited immunodeficiency, eg. X-linked

agammaglobulinaemia. Major Histocompatibility Complex – Study of Twins (MHC), HLA disease associations. Tranplantation, graft –versus-host disease.

Pharmacogenetic – Definition, gene loci influencing drug metabolism and pharmacogenetic interactions

12.00
Unit III: 
UNIT III

 

Extranuclear genetics-Role of organellar genome, maternal inheritance and maternal effect.

Stem cell research and cloning 

Source and isolation of stem cells ,Use of stem cells in human welfare ,Making stem cell lines :Methodology ,Whole body cloning ,Organ Cloning

12.00
Unit IV: 
UNIT IV

 

Human Genome Project 

History, Organization and goals of Human Genome Project 

Human Genome Project  : Friend and Foe ,Repetitive DNA in human genome –Alu and SINE repeats Human genome mapping- Physical, Genetic and Microsatellite mapping,

12.00
Unit V: 
UNIT V

 

Genetic counseling    

Components of genetic counseling, Legal and ethical considerations

risk assessment and counseling in common Mendelian and multifactor syndromes; 

Genetic testing: biochemical & molecular tests: in children, Presymptomatic testing for late onset diseases (predictive medicine); Prenatal and Preimplantation screening  and diagnosis: Indications for prenatal diagnosis, Indications for chromosomal testing, 

Noninvasive methods (Ultrasound, Embryoscopy, MRI, etc.); Invasive methods; Prenatal screening for Down’s syndrome (maternal  serum) & Neural tube defect; Pre-implantation genetic diagnosis; Ethical issues in pre-natal screening & diagnosis.

Study of Eugenics 

    • Negative Eugenics

    • Positive Eugenics

Essential Readings: 

 

  • Snustad& Simmons, Principles of Genetics, 4th Edition, Wiley, 2005.
  • Hartl and Jones, Genetics-Principles and Analysis, 4th Edition, Jones & Bartlett, 1998.
  • Alberts et al, Molecular Biology of The Cell, 2nd Edition , Garland 2007.
  • Lewin, Genes IX, 9th Edition , Jones & Bartlett, 2007.
  • Pastemak, An Introduction to Molecular Human Genetics, 2nd Edition, Fritzgarald, 2005.
  • Mange and Mange, Basic Human Genetics, 2nd Edition, SinauerAssoc, 1999.
  • Vogel and Motulsky, Human Genetics, 3rd Edition, Springer Verlag, 1997.
  • Strachen and Read, Human Molecular Genetics, 3rd Edition, Garland Sci. Publishing, 2004.
  • How1ey and Mori, The Human Genome, Academic Press, 1999.
  • Advanced Molecular Biology Twiman
  • Molecular Cloning Part- 1 Manniatis
  • Molecular Cloning Part - 2 Manniatis
  • Molecular Cloning Part - 3 Manniatis
  • Structural Chemistry and Molecular Biology :Alexander Rich and Norman Davidson
  • The Chemical Foundations of Molecular James D. Watson
  • Biology of the Gene (2nd ed.) Molecular Biology of the Cell :Lewis and Watson
  • Recombinant DNA :Witkowski
  • Genes VI :Benjamin Lewin
  • Principles of gene Manipulation : R. W. Old and Primrose
  • Progress in Nucleic Acid Research and Molecular Biology Vol. 9 J. N. Davidson
  • Genes VII :Benjamin Lewin
  • Human Genetics: Concepts and Applications by Lewis R (2001) McGrawHi; Boston.
  • Basic Human Genetics by E.J. Manage and A.P. Manage (1997 India Reprint) Rastogi Publications, Meerut.
  • Mendelian inheritance in Man: Catalogs of Autosomal recessive, and x-linked phenotypes.[12th editions –1998 ] byMcKusick, V.A. Johns Hopkins university press, Baltimore.
Academic Year: 
2016-2017
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