Biochemistry II

Paper Code: 
ZOL-211
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

OBJECTIVES-

The course objectives to provide students with a basic understanding of:

  1. structural and classification of protein and protein denaturation
  2. Protein and nucleic acid metabolism and their metabolic disorders
  3. Understand  the Bioenergetics of cell
  4. Mineral metabolism in cell.

 

Learning outcomes

By the end of the course, students will be able to:

 

  1. Identify the structural elements of proteins, the basic features of enzyme catalysis and regulation
  2. describe role of protein and nucleic acids in metabolic processes.
  3. Bioenergetics and law of Thermodynamics involved in biological processes.
  4. Role of minerals in metabolism.
9.00

Proteins-

 

  • Classification & structural properties
  • Amino acids & peptides- Properties & structure
  • Configuration:Primary,Secondary,Tertiary,Quaternary
  • Ramachandran  Plot, Protein Sequencing

Protein denaturation

7.00

Proteins Contd-

  • Catabolism of amino acids – Transamination, Transdeamination, Oxidative Deamination and non oxidative deamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)

Inborn errors of Protein metabolism (Alkaptonuria, Phenylketonuria, Maple Syrup, Tyrosinemia, Albinism Urea Disorders)

10.00
  • Nucleic Acid And Nucleotides
  • Structural Properties and Functions
  • Nucleic Acid: Catabolism, Biosynthesis
10.00

Bioenergetics:

  • First and Second law of Thermodynamics
  • Standard free energy change
  • High energy phosphate compounds (ATP, GTP, Creatinine phosphate)
9.00

Mineral Metabolism: (Source, Daily intake, Transportation, Absorption Functions, Deficiency and Diseases)

  • Iodine, Zinc
  • Iron,Calcium,(Transport and Metabolism )
  • Iodine
  • Zinc
  • Iron

Calcium

Essential Readings: 

Essential Readings:

  • Biochemistry; Stryer, L; Freeman Publications.
  • Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R.:  Orient Longman, Madras
References: 

Suggested Readings:

  • Outlines of Biochemistry; Conn, E.E. and Stumpf  P.K. ; John Wiley, New   York.
  • Principles of Biochemistry; Smith; McGraw hill, New York.
  • Biochemistry, D.Voet and J.G.Voet, John Wiley & Sons, (2nd Edition), 1995.
  • Principles of Biochemistry, Lehninger , Nelson and Cox, (3rd Edition), 1999.
  • Principles and Techniques in Biochemistry and Molecular Biology, Edited by Keith Wilson and John Walker, Cambridge University Press, (6th Edition), 2007.
  • Biochemistry and Molecular Biology by W.H. Elliot and Daphne C. Elliot, Oxford University Press, (3rd Edition), 2005.
  • Biochemistry, J. David Rawn, Panima Publishing Corporation, 1st Indian Reprint, 2004.
  • Physical Biochemistry, D Friefelder, W.H. Freeman & Company, 17th Reprint, 1999.
  • Understanding Chemistry, CNR Rao, University Press, Hyderabad 1999.
  • A Biologist's Guide to Principles and Techniques of Practical Biochemistry, K.Wilson& KH Goulding, ELBS Edition 1986.
  • Essentials of Molecular Biology, David Friefelder, Jones and Barllett Publications,7th Reprint, 2001.
Academic Year: 
2019-2020
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