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Biochemistry II
Paper Code:
ZOL-211
Credits:
3
Contact Hours:
45.00
Max. Marks:
100.00
Objective:
OBJECTIVES-
The course objectives to provide students with a basic understanding of:
- structural and classification of protein and protein denaturation
- Protein and nucleic acid metabolism and their metabolic disorders
- Understand the Bioenergetics of cell
- Mineral metabolism in cell.
Learning outcomes
By the end of the course, students will be able to:
- Identify the structural elements of proteins, the basic features of enzyme catalysis and regulation
- describe role of protein and nucleic acids in metabolic processes.
- Bioenergetics and law of Thermodynamics involved in biological processes.
- Role of minerals in metabolism.
9.00
Proteins-
- Classification & structural properties
- Amino acids & peptides- Properties & structure
- Configuration:Primary,Secondary,Tertiary,Quaternary
- Ramachandran Plot, Protein Sequencing
Protein denaturation
7.00
Proteins Contd-
- Catabolism of amino acids – Transamination, Transdeamination, Oxidative Deamination and non oxidative deamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)
Inborn errors of Protein metabolism (Alkaptonuria, Phenylketonuria, Maple Syrup, Tyrosinemia, Albinism Urea Disorders)
10.00
- Nucleic Acid And Nucleotides
- Structural Properties and Functions
- Nucleic Acid: Catabolism, Biosynthesis
10.00
Bioenergetics:
- First and Second law of Thermodynamics
- Standard free energy change
- High energy phosphate compounds (ATP, GTP, Creatinine phosphate)
9.00
Mineral Metabolism: (Source, Daily intake, Transportation, Absorption Functions, Deficiency and Diseases)
- Iodine, Zinc
- Iron,Calcium,(Transport and Metabolism )
- Iodine
- Zinc
- Iron
Calcium
Essential Readings:
Essential Readings:
- Biochemistry; Stryer, L; Freeman Publications.
- Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R.: Orient Longman, Madras
References:
Suggested Readings:
- Outlines of Biochemistry; Conn, E.E. and Stumpf P.K. ; John Wiley, New York.
- Principles of Biochemistry; Smith; McGraw hill, New York.
- Biochemistry, D.Voet and J.G.Voet, John Wiley & Sons, (2nd Edition), 1995.
- Principles of Biochemistry, Lehninger , Nelson and Cox, (3rd Edition), 1999.
- Principles and Techniques in Biochemistry and Molecular Biology, Edited by Keith Wilson and John Walker, Cambridge University Press, (6th Edition), 2007.
- Biochemistry and Molecular Biology by W.H. Elliot and Daphne C. Elliot, Oxford University Press, (3rd Edition), 2005.
- Biochemistry, J. David Rawn, Panima Publishing Corporation, 1st Indian Reprint, 2004.
- Physical Biochemistry, D Friefelder, W.H. Freeman & Company, 17th Reprint, 1999.
- Understanding Chemistry, CNR Rao, University Press, Hyderabad 1999.
- A Biologist's Guide to Principles and Techniques of Practical Biochemistry, K.Wilson& KH Goulding, ELBS Edition 1986.
- Essentials of Molecular Biology, David Friefelder, Jones and Barllett Publications,7th Reprint, 2001.
Academic Year:
