Coming soon
Biochemistry
Course Objectives:
This course will enable the students to
- Develop understanding about properties of water & acid base nature.
- Discriminate between different types of chemical bonds in biomolecules.
- Analyze different aspects of structure and classification of carbohydrates and lipids.
- Describe the principles of bioenergetics and enzyme catalysis.
- Assemble their knowledge and understanding about inborn errors of carbohydrate metabolism, lipid metabolism and vitamins deficiency diseases.
Course Outcomes (COs):
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL 302 |
Biochemistry |
The students will – CO30: Comment on properties of water, acid- base nature, different types of chemical bonds in biomolecules. CO31: Reflect the structure and classification and properties of carbohydrate, proteins and lipids . CO32: Review the principles that govern the structures of macromolecules and their participation in molecular recognition CO33: Correlate the principles of bioenergetics and enzyme catalysis with daily life processes. CO34: Categorize inborn errors of carbohydrate metabolism, lipid metabolism and vitamin deficiency diseases. |
Approach in teaching: Interactive class Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical |
Class test Semester end examinations Quiz Assignments Presentation Individual and group projects |
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Carbohydrates
- Classification, Properties of Monosaccharides,
- Metabolism- Glycolysis, Krebs cycle, Gluconeogenesis, Hexose Monophosphate Pathway Oxidative phosphorylation, Interconversion of glycogen and glucose in liver
Lipids
- Classification,
- Metabolism- Biosynthesis of Palmitic acid, Beta-oxidative pathway of fatty acids
Proteins
- Primary ,Secondary, tertiary and quaternary structure of Proteins, Amino acids- Classification and Structure;
- Catabolism of amino acids- Oxidative Deamination, Transamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)
- pH and Buffers
- Bioenergetics(Thermodynamic laws and ATP);
- Vitamins : Fat soluble & Water soluble vitamins(Source, Function and Deficiency)
Enzymes:
- Classification
- Mechanism of Enzyme action, activation energy
- Kinetics (Michaelis-Menten Equation)
- Factors affecting enzyme action
- Enzyme Inhibition
BOOKS RECOMMENDED:
● U. Satyanarayana . Biochemistry IV Edition, Elsevier (2013)
● Jain,J.L.Fundamentals of Biochemistry ,S.Chand publishers New Delhi.
● Murray, R.K.,Harper's Biochemistry;Appleton and Lange ,Norwalk,Connecticut.
● TextBook of MedicalBiochemistry; Chatterjee, M.N and Shinde, R.; Jaypee brothers.
● Berg, J. M., Tymoczko, J. L. and Stryer, L. (2006). Biochemistry. VI Edition. W.H Freeman and Co.
● Tortora, G.J. and Derrickson, B.H. (2009). Principles of Anatomy and Physiology, XII Edition, John Wiley & Sons, Inc.
● Widmaier, E.P., Raff, H. and Strang, K.T. (2008)
● Principles of Biochemistry; Smith et.al; McGraw Hill, New York.
- Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R; Orient Longman, Madras
- Conn, E.E. and Stuff, P.K. Outlines of Biochemistry,John Wiley New York.
- Donald Voet and Judith G. Voet Biochemistry, John Wiley and Sons., New York.
- LubertStryer, Biochemistry International Student edition W.H. Freeman and Company, New York.
- Metzler, D. Biochemistry, Academic Press.
- Lehninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors, Shahdra, Delhi.
- Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV Edition. W.H. Freeman and Co.
- Murray, R.K., Granner, D.K., Mayes, P.A. and Rodwell, V.W. (2009). Harper’s Illustrated Biochemistry. XXVIII Edition. Lange Medical Books/Mc Graw Hill.
- H.S. Srivastava, Element of Biochemistry, Rastogi Publications Meerut.
