Cell Biology & Genetics I

Paper Code: 
ZOL 102
Contact Hours: 
Max. Marks: 

Course Objectives:

This course will enable the students to

  1. Develop an understanding of the structure and functions of basic components of prokaryotic architecture and eukaryotic cells and their organelles.
  2. Analyzing comprehensive knowledge about an overview of cell theory, role of membrane in transport of molecules across the cell and how these cellular components are used to generate and utilize energy in cells.
  3.  Distinguish between the process of cell division in somatic and germ cells.
  4. Develop understanding of Mendelian inheritance patterns & laws of heredity, Interactions of Genes and their expressions, process of crossing over and linkage in genes etc.

        Course outcomes:


Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL- 102

Cell Biology &

Genetics I

The students will -

CO5: Differentiate the structures and purpose of basic  components of prokaryotic and eukaryotic cells, especially macromolecules, membranes, and organelles.

CO6: Relate the structure, function and composition of the plasma membrane.

CO7: Conceptualise the      importance of nucleus and its components and process of cell division

CO8: Judge how the endoplasmic reticulum and golgi apparatus interact with one another and participate in molecular trafficking in the cell.

CO9: Assemble detailed knowledge about the patterns of Mendelian inheritance and interactions of Genes and their expressions.

CO10: Compare the role of crossing over and linkage in heredity and cytoplasmic inheritance

Approach in teaching:

Class Lectures, Discussion, Tutorials, Reading assignments, Demonstration

Learning activities for the students:

Self-learning assignments, Effective questions, Question preparation,

Seminar presentation, Giving tasks.

Regular Class test Semester end examinations Quiz Solving problems in tutorials Assignments Presentation Individual and group projects


Unit I: 


  • Diversity of Cell Size & shape
  • Cell theory
  • Structure of Prokaryotic & Eukaryotic cells
  • Cell membrane structure and function
  • Active and Passive transport across membranes
  • Pinocytosis, Phagocytosis, Endocytosis, Exocytosis


Unit II: 

Cell organelles, their structure, composition & function

  • Endoplasmic reticulum
  • Golgi complex
  • Ribosome : structure & functions
  • Lysosomes: Function & intracellular digestion
  • Mitochondria: Organization &function, and Oxidative phosphorylation
  • Peroxisomes
  • Centrioles & Microtubules: cilia & flagella


Unit III: 



  • Nucleus structure: Structure & function of nuclear envelope, nuclear matrix and nucleolus
  • Cell cycle( S, G1,G2,M phase)
  • Mitosis: Phases & process of mitosis
  • Meiosis: Phases & Process of meiosis


Unit IV: 


Concepts of Genetics

  • Mendelian inheritance patterns & laws of heredity
  • Co and incomplete dominance
  • Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
  • Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
  • Gene expression- Lethal genes, Pleiotropic genes
  • Multiple genes- skin colour in human


Unit V: 


  • Linkage & construction of linkage maps
  • Crossing over- Mechanism, theories, Cytological detection & significance
  • Cytoplasmic inheritance
Essential Readings: 



●    Cell Biology by C.B. Powar; Himalaya Publishing House.

●    Cell and Molecular Biology; Phillip Sheeler Donald E. Bianchi; John Wiley and Sons.

●    The Cell: A Molecular Approach. Cooper, G. Houseman G.R. SinaeurAssoc, New York.

●    Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.

●    Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc

●    Essentials cell Biology II Ed., Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishing.

●    Genetics; Winchester, A.M; Oxford and IBH Publishing Co.


Academic Year: