Toxicology

Paper Code: 
LSC 143 B
Credits: 
04
Contact Hours: 
60.00
Max. Marks: 
100.00
10.00
History and scope of Toxicology
 
   1.    Environmental Toxicology
 
   2.    Economic Toxicology
 
   3.    Forensic Toxicology
 
Different areas of Toxicology
 
Classification of Toxic Agents 
15.00
Disposition of Toxicants
• Absorption, Distribution & Excretion of Toxicants 
Mechanisms of Toxicity
• Delivery
• Absorption
• Distribution
• Excretion
• Cellular Dysfunctions and resultant toxicities
• Repair or Dysrepair
Biotransformation of Xenobiotics
• Phase I Enzymes (Hydrolysis, Reduction, Oxidation)
• Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acelylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation )                             
15.00
Target Organ Toxicity 
• Liver
• Blood
Physicochemical nature & Effect of Toxic Agents
• Pesticides
• Metals
• Bioaccumulation and Biomagnification of Toxicants
 
10.00
Non-Organ-Directed Toxicity
• Chemical Carcinogenesis 
• Genetic Toxicology 
 
10.00
Environmental Toxicology 
• Air Pollution 
• Ecotoxicology : Chemodynamics, Biomarkers,
                           Terrestrial and Aquatic Ecotoxicology  
 
Essential Readings: 

Books Recommended:

  • Casarett and Daull’s Toxicology: The basic science of poisons. By : Curtis D. Klaassen 6th Edn., McGraw-Hill (Medical Publishing Div. NewYork
  • Environmental Biotechnology – by. Indu Shekhar Thakur, I.K. International Pub.(2006)
  • Toxicology, Principles and Applications: Raymond I.M.. CRC Publication.
  • Microbial Ecology: Fundamentals and Applications by Atlas Bartha (An imprint of Addison Wesley Longman Inc)
  • Environmental Microbiology: Maier R.M., Academic Press. 2000 Press, Cambridge. 1993.
  • Environmental Science- A global concern; Cunningham W.P. and Saigo B.W Win. C. Brown Publishers, London, 1995.
  • Advances in Industrial Waste Water Treatment; P.K. Goel; Technoscience Publications. Jaipur, 1999.
  • An Introduction to Air Pollution; Trivedy R.K. and Goel P.K., Technoscience Publications, Jaipur, 1995.
  • Problems of Environment Management in India; Goel M.M., Sharma M.C. and Purohit N.K; Anupriya Publishing House, Jaipur, 1999.
  • Environmental Science (A study of interrelations); Enger E.D. and Smith B.F.;  Win. C. Brown Pub. (Latest Edition). 
  • Botkin D. And Keller E. Environmental Science. Earth as a Living Planet; Botkin D. And Keller E

 

Academic Year: 
2025-2026
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