SPECIAL PAPER: CANCER AND RADIATION BIOLOGY II

Paper Code: 
ZOL 423 A
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course objectives:

This course will enable the students to -

  1. To provide a detailed knowledge of types of cancer and their causes.
  2. Role of radiations in cancer and their treatment.

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 423A

 

Cancer And Radiation Biology II

Students should be able to describe

CO97: Types of cancer and their causes

CO98: Role of radiations in cancer and their treatment.

CO99: Radiation safety and regulator aspects.

 

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching

 

Learning activities for the students:

Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

Class test

Semester end examinations,

Quiz

Assignments,

Presentations

Surprise test

Open book test

 

12.00
Unit I: 
UNIT I

Causation of cancer :

  •     Hereditary cancer.
  •     Virus and cancer
  •     Chemical carcinogenesis
  •     Hormones and cancer
  •     Nutrition and cancer
  •     Radiation carcinogenesis:Basic concept of free radicals and their role in cancer
12.00
Unit II: 
UNIT II

Therapy of cancer.

  •     Surgical removal.
  •     Chemotherapy
  •     Radiotherapy.
  •     Immunotherapy.
  •     Hyperthermia

    Management of therapy of cancer.

    Prevention of cancer.

  •     Primary prevention : Education, motivation, legislation.
  • Secondary prevention: Detection of precancerous and early cancerous lesion, Chemoprevention.

 

12.00
Unit III: 
UNIT III

Acute radiation effects.

  •     Concept of LD50.
  •     Central nervous system syndrome.
  •     Gastro-intestinal syndrome.
  •     Bone.marrow syndrome.
  •     Skin reactions.
12.00
Unit IV: 
UNIT IV

Delayed effects of Radiation.

  •     Stochastic and deterministic effects.
  •     Radiologic aging,
  •     Life shortening.
  •     Radiation carcinogenesis.
12.00
Unit V: 
UNIT V

Radiation safety and regulator aspects.

  •     Radiographic installations.
  •     Enclosed installations.
  •        Field installations.
  •     Personnel management.
  •     Source storage facilities.
  •     Safe work practice.
  •       Re-commendations of National/international statutory bodies
Essential Readings: 

Suggested Readings :

  •     RameshaRao. : Who runs the risk of cancer.Shipra Publication.
  •     Alberts.  B.  Bras  D.  lenis J.   :  Molecular Biology of the  cells.  Govland Publishing New York.
  •     Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B. Lippincott.
  •     Hall. E. J. Radiobiology for the radiobiologists. Lippincott. Philadelphia.
  •     P.S. Lotran. V. Kumar. T.collins. : Pathology of Diseases Robbins.
  •     Peekham.   M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of  oncology Vol. I.. Vol.  II. Oxford Medical Publication. Oxford University  Press. Inc. New York 1995.
  •     Tannode.  1  F  and  Richand  P.   :  The  Basic  science  of oncology.  ThII.MacGraw-Hill
  •     Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology Thomson press Ltd.. NOIDA. 1999.
  •     Weiss. L. : Principles of metastases. Acdemic press.
Academic Year: 
2020-2021
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