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Molecular Biology & Genetics II
Paper Code:
ZOL 202
Credits:
3
Contact Hours:
45.00
Max. Marks:
100.00
9.00
Unit I:
UNIT I
- Nuclear Organization:
- Structure & function of nuclear envelope, nuclear matrix and nucleolus
- Chromosomes: Morphology, Chromonema, Chromomeres, telomeres, Primary & secondary constrictions, Chromatids
- Chromosome type- Polytene & Lampbrush
- Chromosomal Organization: euchromatin, Heterochromatin , nucleosome concept
7.00
Unit II:
UNIT II
- DNA structure(A, B, Z type)
- Experiments of Messelson & Stahl
- Replication(Semi-conservative mechanism)
Elementary idea about Polymerases,Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments,
10.00
Unit III:
UNIT III
- RNA structure & types( mRNA, rRNA, tRNA)
- Transcription(Idea about Polymerases)
- Genetic code &
- Translation – Basic idea about Protein synthesis
10.00
Unit IV:
UNIT IV
|
9.00
Unit V:
UNIT V
- Mutations- Chromosomal aberrations, Gene mutations
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Essential Readings:
- Genetics; Winchester, A. M.; Oxford and IBH Publishing Co.
- Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
- Genetics; Strickberger W. M.; Prentice Hall of India.
- Cell Biology; Powar, C.B; Himalayan Publishing House.
- Principles of Genetics; Gardener, E. J.;Wiley eastern, New Delhi.
- A Textbook of Genetics; Rastogi, V.B.; Ramnath and Kedarnath
- Molecular Biology of the gene; Watson, J.D; Benzamin/ Cummings.
- Biochemistry; Voet &Voet; John Wiley & Sons.
- Cytology and Genetics. Dyansagar, C.R. Tata McGraw Hill Publ. Co. New Delhi.
- Cell Biology : Dyson, R.D. Allen and Bacon, New York.
- Cell Biology. Rastogi S.C. : Tata McGraw Hill Publ. Co. New Delhi.
- Cell Biology and Genetics. Kohli, S. jain, S. and Ramesh Book Depot. Jaipur.
- Cytology : Verma, P.S. and Agrawal V.K : S.Chand and Co. New Delhi.
- Genetics. Verma, P.S. and Agrawal V.K. S.Chand and Co., New Delhi
Academic Year:
