Molecular Biology & Genetics II

Paper Code: 
ZOL-202
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
9.00
  • Nuclear Organization:
  • Structure & function of nuclear envelope, nuclear matrix and nucleolus
  • Chromosomes: Morphology, Chromonema, Chromomeres, telomeres, Primary & secondary constrictions, Chromatids
  • Chromosome type- Polytene & Lampbrush
  • Chromosomal Organization: euchromatin, Heterochromatin ,  nucleosome concept
7.00

·        DNA structure(A, B, Z type)

·        Experiments of Messelson & Stahl

·        Replication(Semi-conservative mechanism)

Elementary idea about Polymerases,Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments,

10.00
  • RNA structure & types( mRNA, rRNA, tRNA)
  •  Transcription(Idea about Polymerases)
  • Genetic code &

Translation – Basic idea about  Protein synthesis

10.00
  • Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory, Non disjunction in man
 

Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes

9.00
  • Mutations- Chromosomal aberrations, Gene mutations
  • Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis
  • Human betterment- Eugenics & Euthenics
 
Essential Readings: 
  • Genetics; Winchester, A. M.; Oxford and IBH Publishing Co.
  • Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
  • Genetics; Strickberger W. M.; Prentice Hall of India.
  • Cell Biology; Powar, C.B; Himalayan Publishing House.
  • Principles of Genetics; Gardener, E. J.;Wiley eastern, New Delhi.
  • A Textbook of Genetics; Rastogi, V.B.; Ramnath and Kedarnath
  • Molecular Biology of the gene; Watson, J.D; Benzamin/ Cummings.
  • Biochemistry; Voet &Voet; John Wiley & Sons.
  • Cytology and Genetics. Dyansagar, C.R. Tata McGraw Hill Publ. Co. New Delhi.
  • Cell Biology : Dyson, R.D. Allen and Bacon, New York.
  • Cell Biology. Rastogi S.C. : Tata McGraw Hill Publ. Co. New Delhi.
  • Cell Biology and Genetics. Kohli, S. jain, S. and Ramesh Book Depot. Jaipur.
  • Cytology : Verma, P.S. and Agrawal V.K : S.Chand and Co. New Delhi.
  • Genetics. Verma, P.S. and Agrawal V.K. S.Chand and Co., New Delhi.

 

 

 

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