Molecular Biology

Paper Code: 
ZOL-213
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
9.00

Chromosomes: Morphology, Chromonema, Chromomeres, Telomeres, Primary & secondary constrictions, Chromatids

Chromosome type- Polytene & Lampbrush

 

Chromosomal Organization: Euchromatin, Heterochromatin , Nucleosome concept

7.00

Nucleosides, Nucleotides

DNA, RNA

DNA structure(A, B, Z type)

 

Experiments of Messelson & Stahl

10.00



Replication of prokaryotes (Semi-conservative mechanism)

Prokaryotic Polymerases,Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments

10.00

RNA structure & types( mRNA, rRNA, tRNA)

 Prokaryotic Transcription: RNA Polymerases, Transcription factors.

  • Transcription termination
  • Mechanism of transcription
 

Post Transcriptional modification in RNA

9.00

Translation

Genetic Code

Prokaryotic translation

Translational Machinery

 

Translational Initiation, Elongation and termination

Essential Readings: 

ü  Becker, W.M., Kleinsmith, L.J., Hardin. J. and Bertoni, G. P. (2009). The World of the Cell. VII Edition. Pearson Benjamin Cummings Publishing, San

ü  Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts,

ü  Peter Walter: Molecular Biology of the Cell, IV Edition.

ü  Cooper G. M. and Robert E. Hausman R. E. The Cell: A Molecular Approach, V Edition, ASM Press and Sinauer Associates.

ü  De Robertis, E.D.P. and De Robertis, E.M.F. (2006). Cell and Molecular Biology. VIII Edition. Lippincott Williams and Wilkins, Philadelphia.

ü  Karp, G. (2010) Cell and Molecular Biology: Concepts and Experiments. VI Edition. John Wiley and Sons. Inc.

ü  Lewin B. (2008). Gene XI, Jones and Bartlett

ü   McLennan A., Bates A., Turner, P. and White M. (2015). Molecular Biology IV Edition. GS, Taylor and Francis Group, New York and London.

ü   Molecular Biology of the gene; Watson J.D.; Benzamin/ Cummings.

ü   Molecular Cell biology (2nd Edition) J. Darnell, H. Lodish and D.Baltimore, Scientific American Books,USA,1994.

ü   Cell & Molecular Biology, (8th edition), E D P Roberties & E M F Roberties,  Lippincott Williams & Wilkins, 2005

ü   Cell and Molecular Biology, (3rd edition), P Sheeler and D E Bianchi, John Wiley & Sons, Inc, 1987

ü   The cell. A Molecular Approach, (4th edition), G H Cooper and R E Hausman, ASM Press, 2007

Academic Year: