Molecular Biology

Paper Code: 
ZOL 213
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
9.00
Unit I: 
UNIT I

Chromosomes: Morphology, Chromonema, Chromomeres, Telomeres, Primary & secondary constrictions, Chromatids

Chromosome type- Polytene & Lampbrush
 

Chromosomal Organization: Euchromatin, Heterochromatin , Nucleosome concept

7.00
Unit II: 
UNIT II

Nucleosides, Nucleotides

DNA, RNA

DNA structure(A, B, Z type)
 

Experiments of Messelson & Stahl 

10.00
Unit III: 
UNIT III

Replication of prokaryotes (Semi-conservative mechanism)
 

Prokaryotic Polymerases,Topoisomerases, Single stranded binding protein, Replication forks(Unidirectional & Bidirectional), Leading & lagging strand, RNA primers & Okazaki fragments

9.00
Unit IV: 
UNIT IV

RNA structure & types( mRNA, rRNA, tRNA)

 Prokaryotic Transcription: RNA Polymerases, Transcription factors.

·         Transcription termination

·         Mechanism of transcription
 

Post Transcriptional modification in RNA

10.00
Unit V: 
UNIT V

Translation

Genetic Code

Prokaryotic translation

Translational Machinery

Translational Initiation, Elongation and termination

 

Academic Year: 
2016-2017
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