MICROBIOLOGY

Paper Code: 
ZOL-502
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

OBJECTIVES-

  1. The student will be able to identify common infectious agents and the diseases that they cause.
  2. The students will learn about the nutritional requirements of microbes.
  3. The student will be able to explain general and specific mechanisms by which an infectious agent causes disease.

Learning Outcomes-

  1. The student will be able to describe the epidemiology of infectious agents including how infectious diseases are transmitted.
  2. The students will be able to culture the microbes.
  3. The student will be able to explain interventions employed to prevent infectious diseases including infection control measure and vaccines
9.00
Unit I: 
UNIT I

Brief introduction to the history of Microbiology

  • Work of Anton Van Leeuwenhoek
  • Work of Louis Pasteur, John Tyndall, Robert Koch & Jenner

Prokaryota(Bacteria)

  • Size, shape & pattern of arrangement

Structural Organization—Slime layer(Capsule) Cell envelope, Cytoplasmic membrane(Inner membrane), Cell wall(Outer membrane) of gram-ve& gram +ve bacteria, Mesosomes; Cytoplasmic organization, Cell projections- Flagella & pili

10.00
Unit II: 
UNIT II

Genetic material of bacteria: Chromosomes, Plasmids, Replication of bacterial DNA

Reproduction in Bacteria: Asexual reproduction: Binary fission, budding, Endospore formation& cyst formation Transformation, Conjugation,

Transduction & Bacterial recombination

8.00
Unit III: 
UNIT III

Microbial nutrition culture of Bacteria

  • Carbon & energy source
  • Nitrogen & minerals
  • Organic growth factors
  • Oxygen
  • Environmental factors: Temperature, Hydrogen ion concentration, Osmotic pressure

 Microbial growth

10.00
Unit IV: 
UNIT IV

Bacteria of medical importance:

Gram +ve:

  • Cocci : Staphylococci, Streptococci
  • Bacilli: Diptheria, Tetanus

Gram –ve:

  • Cocci: Gonorrhea, Meningitis
  • Bacilli: Diarrhoea

Mycobacteria: Tuberculosis

Hepatitis (with emphasis on B type)

The causative agents, Transmission, Pathogenicity, Laboratory diagnosis, Treatment & Prevention

8.00
Unit V: 
UNIT V
  • Cyanobacteria(Structural organization and significance),
  • Yeast- industrial application
  • Virus : General Characteristics, structure, classification on the basis of morphology and genetic material

Lytic & Lysogenic cycles

Essential Readings: 
  • P.D. Sharma, Microbiology,Rastogi and Company, Merrut.
  • Microbiological Application,AlfredE.Brown, McGraw.Hill
  • Microbiology by Totora, Pearson Education.
References: 
  • Microbial:T.StuartWalker,W.B.Saunders Company
  • Microbiological Application,AlfredE.Brown, McGraw.Hill
  • Practical Biochemistry:Principles&Techniques; Keith Wilson& John Walker;CambridgeUniversity Press.
  • Lechiman, W.Microbiology, Glenced Pub1. Co.New York
  • Nestler, R.L. Microbiology, W.S. Saunders, Philadelphia (Student edition:Holt-Saunders International Edition, Tokyo).
  • Salle,S.J. Fundamental Principles of Bacteriology,TataMcGraw Hill Pub. Co., New Delhi.
  • Stonier, T.I. Nouderroff, and Adeloverg, E.A. General Microbiology.
  • Jaceb D. AvumVyas A.D.K. Parichayaksuchmjeevvigyan, Ramesh Book Depot,Jaipur
  • Jacob D.IntroductoryMicrobiology,Ramesh Book Depot,Jaipur.
  • Cruick shank et al. Medical Microbiology.The English Language Book Society,London.
  • P.D. Sharma, Microbiology,Rastogi and Company, Merrut.
  • David Freifelder-Molecular Biology, Narosa Publishing House, New Delhi.
Academic Year: 
2019-2020
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