Immunology

Paper Code: 
DZOL501A T
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

DZOL501A

 

 

Immunology

 

The students will be able to-

CO 1: Distinguish primary and secondary lymphoid organs of the Immune system.

CO 2: Examine & interpret various forms of  antibody-antigen interactions, autoimmune diseases and the concept of antigen.

CO 3: Investigate the structure,types and functions of Immunoglobulin,

CO 4 : Distinguish the major cellular and tissue components which comprise the innate and adaptive immune system. compare and contrast  how immune responses by CD4 and CD8 T cells, and B cells are initiated and regulated.

 

 

Approach in teaching: Discussion, Demonstration, Action Research, Project, Field Trip

Learning activities for the students:Field activities, Simulation, Presentation, Giving task

Class test

Semester end examinations,

 Quiz,

Assignments,

Seminar Presentation

Individual and group projects

 

12.00
Unit I: 
UNIT I
Overview of Immune System & Antigens
Historical perspective of Immunology,
Early theories of Immunology, 
Cells and organs of the Immune system
Antigenicity and immunogenicity, Immunogens,
Adjuvants and haptens,
Factors influencing immunogenicity
B and T-Cell epitopes
16.00
Unit II: 
Unit II
Innate and Adaptive Immunity 16 Hrs
Innate immunity-Anatomical barriers, Inflammation, Cell and molecules involved in innate immunity
Adaptive immunity-Cell mediated and humoral immunity
Immune dysfunctions (brief account of autoimmunity with reference to Rheumatoid
Arthritis and tolerance, AIDS).
Passive: Artificial and natural Immunity, Active: Artificial and natural Immunity,
Vaccines and its types
 
12.00
Unit III: 
Unit III
Immunoglobulins   
Structure and functions of different classes of immunoglobulins,
Antibody mediated effector functions
Antigen antibody interactions, Immunoassays (ELISA and RIA), Polyclonal sera,
Hybridoma technology: Monoclonal antibodies in therapeutics and diagnosis
12.00
Unit IV: 
Unit IV
Major Histocompatibility Complex & Cytokines
Structure and functions of MHC molecules. 
Endogenous and exogenous pathways of antigen processing and presentation
Properties and functions of cytokines, Therapeutics Cytokines
8.00
Unit V: 
Unit V
Complement System & Hypersensitivity    8 Hrs 
Components and pathways of complement activation.
Gell and Coombs’ classification and brief description of various types of hypersensitivities
Essential Readings: 
Roitt’s essential Immunology, P. Delves, et al., 11th ed., Blackwell Publishing, 2006
• Kindt, T. J., Goldsby, R.A., Osborne, B. A. and Kuby, J (2006). Immunology, VI Edition.
W.H. Freeman and Company.
 
SUGGESTED READINGS:
• David, M., Jonathan, B., David, R. B. and Ivan R. (2006). Immunology,VII Edition,
Mosby, Elsevier Publication.
• Abbas, K. Abul and Lechtman H. Andrew (2017) Cellular and Molecular Immunology.
V Edition. Elsevier; 9th edition
 
e-RESOURCES:
• Immunology- ePG pathshala- Inflibnet centre-
 
e-JOURNAL:
• Immunology- Wiley online Library- ISSN 1365-2567
• Scandinavian Journal of Immunology-Online ISSN: 1365-3083
Academic Year: 
2023-2024
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