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IMMUNOLOGY
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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DZOL511A |
IMMUNOLOGY |
The students will be able to-
CO 1: Distinguish primary and secondary lymphoid organs of the Immune system. CO 2 : Examine & interpret various forms of antibody-antigen interactions, autoimmune diseases and the concept of antigen. CO 3: Investigate the structure,types and functions of Immunoglobulin, CO 4: Distinguish the major cellular and tissue components which comprise the innate and adaptive immune system. compare and contrast how immune responses by CD4 and CD8 T cells, and B cells are initiated and regulated. |
Approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching
Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical |
Class test Semester end examinations, Quiz Assignments Presentation Individual and group projects |
Overview of Immune System & Antigens
Historical perspective of Immunology,
Early theories of Immunology,
Cells and organs of the Immune system
Antigenicity and immunogenicity, Immunogens,
Adjuvants and haptens,
Factors influencing immunogenicity
B and T-Cell epitopes
Innate and Adaptive Immunity
Innate immunity-Anatomical barriers, Inflammation, Cell and molecules involved in innate immunity
Adaptive immunity-Cell mediated and humoral immunity
Immune dysfunctions (brief account of autoimmunity with reference to Rheumatoid
Arthritis and tolerance, AIDS).
Passive: Artificial and natural Immunity, Active: Artificial and natural Immunity,
Vaccines and its types
Immunoglobulins
Structure and functions of different classes of immunoglobulins,
Antibody mediated effector functions
Antigen antibody interactions, Immunoassays (ELISA and RIA), Polyclonal sera,
Hybridoma technology: Monoclonal antibodies in therapeutics and diagnosis
Major Histocompatibility Complex & Cytokines
Structure and functions of MHC molecules.
Endogenous and exogenous pathways of antigen processing and presentation
Properties and functions of cytokines, Therapeutics Cytokines
Complement System & Hypersensitivity
Components and pathways of complement activation.
Gell and Coombs’ classification and brief description of various types of hypersensitivities
ESSENTIAL READINGS:
● Roitt’s essential Immunology, P. Delves, et al., 11th ed., Blackwell Publishing, 2006
● Kindt, T. J., Goldsby, R.A., Osborne, B. A. and Kuby, J (2006). Immunology, VI Edition.
W.H. Freeman and Company.
SUGGESTED READINGS:
● David, M., Jonathan, B., David, R. B. and Ivan R. (2006). Immunology,VII Edition,
Mosby, Elsevier Publication.
● Abbas, K. Abul and Lechtman H. Andrew (2017) Cellular and Molecular Immunology.
V Edition. Elsevier; 9th edition
e-RESOURCES:
Immunology- ePG pathshala- Inflibnet centre-
https://epgp.inflibnet.ac.in/Home/ViewSubject?catid=2rAs1Puvga4LW93zMe83...
Immunology- NPTEL- https://nptel.ac.in/courses/102103038
e-JOURNAL:
● Immunology- Wiley online Library- ISSN 1365-2567
● Scandinavian Journal of Immunology-Online ISSN: 1365-3083
