Immunology

Paper Code: 
ZOL 512
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

 

 

 

Course objectives:

This course will enable the students to -

  1. To get insight into Primary and Secondary organs of the Immune system.
  2. To describe antibody-antigen interaction, Autoimmune diseases, the concept of antigen, antigenic determinants, hapten, factors affecting antigenicity
  3. Immunoglobulin, structure, types, and functions
  4. To identify the major cellular and tissue components which comprise the innate and adaptive immune system. Understand how are immune responses by CD4 and CD8 T cells and B cells initiated and regulated.
  5. Understand how the immune system distinguishes self from non-self.

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

ZOL 512

Immunology

Students will be able

CO 86: To get insight into Primary and Secondary organs of the Immune system.

CO 87: To describe antibody-antigen interaction, Autoimmune diseases, the concept of antigen, antigenic determinants, hapten, factors affecting antigenicity

CO 88: Immunoglobulin, structure, types and functions

CO 89: Identify the major cellular and tissue components which comprise the innate and adaptive immune system.  Understand how are immune responses by CD4 and CD8 T cells, and B cells initiated and regulated.

The approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations, Explanation by videos

 

 

Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

 

Class test

Semester end examinations,

Quiz,

Assignments,

Presentation

Surprise test

Open book test

 

 

7.00
Unit I: 
UNIT I

Immunology
Definition
Types of immunity: innate and acquired
Antigen: Antigenicity of molecules, Immunogenicity and its properties, haptens, adjuvants

8.00
Unit II: 
UNIT II

Antibody

  • Definition.
  • Structure , effector function
  • (IgG. IgM. IgD. IgA and IgE)
  • Properties and function of each class of immunoglobulin.
  • Isotype, Allotype, Ideotype

Antigen-antibody reactions

  • Precipitation reaction
  • Agglutination reaction
10.00
Unit III: 
UNIT III

Cells  and organs of Immunity

  • Primary and Secondary lymphoid organs
  • Dendritic cells
  • Macrophages.
  • Lymphocytes (B- and T- types). T.- Helper cells. T-killer cells, plasma cells and memory cells

 

12.00
Unit IV: 
UNIT IV

MHC genes and gene products.
Mechanism of Humoral& Cell mediated  immune response
Complement and its action

8.00
Unit V: 
UNIT V
  • Autoimmunity : Hashimoto thyroiditis, Myasthenia gravis, Rheumatoid arthritis, Lupus
  • Immunodeficiency: AIDS- causes, symptoms, treatment, mode of infection, HIV lifecycle
  • Hypersensitivity-  Type I to IV
  • Cvtokines:  Types, Properties and Function.

 

Essential Readings: 
  • Kuby, Immunology, W.H. Freeman and Company.

Suggested Readings:

  • D.M. Wear, Immunology ELBS (English) Language Book Society Low  Priced edition, Longman Singapore Publishers Ltd.
  • Iyan M. Roitt Essential Immunology EIBS Low Priced Edition Black
  • Kindt, T. J., Goldsby, R.A., Osborne, B. A. and Kuby, J (2006).  Immunology, VI  Edition. W.H. Freeman and Company.
  • David, M., Jonathan, B., David, R. B. and Ivan R. (2006).  Immunology,VII Edition, Mosby, Elsevier Publication.
  • Abbas, K. Abul and Lechtman H. Andrew (2003.) Cellular and Molecular  Immunology. V Edition. Saunders Publication.

 

Academic Year: 
2020-2021
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