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Genetics & Biostatistics
Paper Code:
ZOL-214
Credits:
3
Contact Hours:
45.00
Max. Marks:
100.00
9.00
Unit I:
UNIT I
Mendelian inheritance patterns & laws of heredity
Co and incomplete dominance
Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
Gene expression- Lethal genes, Pleiotropic genes
Multiple genes- Seed coat in wheat, skin colour in human
7.00
Unit II:
UNIT II
Linkage & linkage maps
Crossing over- Mechanism, theories, Cytological detection & significance
Cytoplasmic inheritance
Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis
Human betterment- Eugenics & Euthenics
10.00
Unit III:
UNIT III
Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory, Non disjunction in man
Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes
Mutations- Chromosomal aberrations, Gene mutations
10.00
Unit IV:
UNIT IV
Introduction, scope and application of Biostatistics
Frequency distribution
Graphical presentation of data
9.00
Unit V:
UNIT V
Mean. mode, median and their significance
Standard deviation ,variance and coefficient of variance
Tests of significance- t-test(1 population & 2 population test), Chi-square( independence of attributes)
Simple correlation (Karl Pearson method) & regression
Essential Readings:
Genetics; Winchester, A. M.; Oxford and IBH Publishing Co.
Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
Genetics; Strickberger W. M.; Prentice Hall of India.
Principles of Genetics; Gardener, E. J.;Wiley eastern, New Delhi.
A Textbook of Genetics; Rastogi, V.B.; Ramnath and Kedarnath
Molecular Biology of the gene; Watson, J.D; Benzamin/ Cummings.
Cytology and Genetics. Dyansagar, C.R. Tata McGraw Hill Publ. Co. New Delhi.
Genetics. Verma, P.S. and Agrawal V.K. S.Chand and Co., New Delhi.
Biostatistics: A Foundation for Analysis in Health Sciences, (6th edition), W W Daniel, John Wiley and Sons Inc., 1995.
Statistical Methods in Biology, N T J Bailey, Cambridge University Press, 1995.
Statistics for Biologist, R C Campbell, Cambridge University Press, 1989.
Fundamentals of Biostatistics, Khan, Publishing Corporation, 1999
Practical statistics for Experimental Biologists, A C Swardlaw, John Wiley and sons Inc., 1985
Academic Year:
