Genetics & Biostatistics

Paper Code: 
ZOL 214
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
9.00
Unit I: 
UNIT I

Mendelian inheritance patterns & laws of heredity

Co and incomplete dominance

Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)

Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh

Gene expression- Lethal genes, Pleiotropic genes

 

Multiple genes- Seed coat in wheat, skin colour in human

7.00
Unit II: 
UNIT II

Linkage & linkage maps

Crossing over- Mechanism, theories, Cytological detection & significance

Cytoplasmic inheritance

Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis

 

Human betterment- Eugenics & Euthenics

10.00
Unit III: 
UNIT III

Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory, Non disjunction in man

Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes

 

Mutations- Chromosomal aberrations, Gene mutations

10.00
Unit IV: 
UNIT IV

Introduction, scope and application of Biostatistics

Frequency distribution

 

Graphical presentation of data

9.00
Unit V: 
UNIT V

Mean. mode, median and their significance

Standard deviation ,variance and coefficient of variance

Tests of significance- t-test(1 population & 2 population test), Chi-square( independence of attributes)

 

 

Essential Readings: 
  • Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
  • Genetics; Strickberger; Macmillan, Prentice Hall of India.
  • Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
  • Primose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, Willey- Blacwell.
  • Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
  • A Textbook of Genetics; Rastogi, V.B.; Ramnath & Kedarnath.
  • Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings  
  • Cell and Molecular Biology; Phillip Sheeler,   Donald E. Bianchi; John Wiley and Sons.
  • Biostatistics; Gupta, S.P.;Sultan Chand &Co.
  • Bencroft, H. Introduction to Biostatistics Harper and Row. New York, 1957.
  • Bailey, N.T.J. Statistical method in Biology Low Priced Text Book English Language Society, London, 1959.
  • Bishop O.N. Statistics for biology, Prentice Hall Press
  • Mahajan B.K., Methods in Biostatistics, Jaypee.
  • Practical Exercises in Cytology, Genetics, Plant Breeding and Biostatistics. Raghuvanshi.

 

 

Academic Year: