Course objectives:
This course will enable the students to -
1. Develop detailed knowledge of Mendelian inheritance and interactions of Genes
2. Analyze crossing over and linkage in heredity and chromosome mapping.
3. Perceive the concept of sex determination.
4. Acquire the knowledge about origin of life and concept of speciation
Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
|
Course Code |
Course Title |
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25CZOL 401 |
GENETICS AND EVOLUTIONARY BIOLOGY |
CO 37: Outline detailed knowledge about the patterns of Mendelian inheritance and interactions of Genes and their expressions. CO 38: Compare the role of crossing over and linkage in heredity and acquire knowledge about sex linked inheritance, cytoplasmic inheritance and polygenic inheritance. CO 39:Perceive the concept of mutation and sex determination CO 40: Acquire knowledge on evolutionary theories and evidences of evolution and process of evolutionary change CO 41: Build the concept of Natural selection,speciation and macroevolution CO42:Contribute effectively in course- specific interaction |
The approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Chart preparation |
Assessment Strategies Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation. |
Introduction to Genetics: Mendel’s work on transmission of traits
Mendelian Genetics and its Extension: Principles of Inheritance, Chromosome theory of inheritance, Incomplete dominance and codominance, Multiple alleles, Lethal alleles, Epistasis, Pleiotropy
Sex linked inheritance, extra-chromosomal inheritance, Polygenic inheritance, Linkage, Crossing Over, Recombination frequency as a measure of linkage intensity
Mutations - Chromosomal Mutations: Deletion, Duplication, Inversion, Translocation, Aneuploidy and Polyploidy
Gene mutations: Induced versus Spontaneous mutations, Back versus Suppressor mutations
Sex Determination: Environmental sex determination & Chromosomal mechanisms
Lamarckism, Darwinism, Neo-Darwinism
Direct Evidences of Evolution: Types of fossils, Incompleteness of fossil record Processes of Evolutionary Change: Organic variations
Isolating Mechanisms
Natural selection (Example: Industrial melanism); Artificial selection
Species Concept: Biological species concept (Advantages and Limitations); Modes of speciation (Allopatric, Sympatric)
Macro-evolution: Macro-evolutionary Principles (example: Darwin’s Finches)
● Gardner, E.J., Simmons, M.J., Snustad, D.P. (2008). Principles of Genetics. VIII Edition. Wiley India.
● Snustad, D.P., Simmons, M.J. (2009). Principles of Genetics. V Edition. John Wiley and Sons Inc.
● Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
● Genetics; Strickberger; Macmillan, Prentice Hall of India.
● Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
● Primrose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, WilleyBlacwell.
● BenjaminCummings Russell, P. J. (2009). Genetics- A Molecular Approach.III Edition. ∙ BenjaminCummings Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C. and Carroll, S.B. Introduction to Genetic Analysis. IX Edition.
● Evolution, V.B.Rastogi, Kedar Nath, Ram Nath, Merrut. Genes and Evolution. JhaA.P John Publication, New Delhi
● Klug, W.S., Cummings, M.R., Spencer, C.A. (2012). Concepts of Genetics. X Edition. Benjamin Cummings.
● Russell, P. J. (2009). Genetics- A Molecular Approach. III Edition. Benjamin Cummings.
● Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C. and Carroll, S.B. Introduction to Genetic Analysis. IX Edition.
● W. H. Freeman and Co. Ridley, M. (2004). Evolution. III Edition. Blackwell Publishing ∙ Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B. and Patel, N. H. (2007). Evolution. Cold Spring, Harbour Laboratory Press.
● Hall, B. K. and Hallgrimsson, B. (2008). Evolution. IV Edition. Jones and Bartlett Publishers
● W. H. Freeman and Co. Ridley, M. (2004). Evolution. III Edition. Blackwell Publishing ∙ Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B. and Patel, N. H. (2007). Evolution. Cold Spring, Harbour Laboratory Press.
● Hall, B. K. and Hallgrimsson, B. (2008). Evolution. IV Edition. Jones and Bartlett Publishers
● Campbell, N. A. and Reece J. B. (2011). Biology. IX Edition, Pearson, Benjamin, Cummings.
● Genetics and Origin of Species. Dobzhansky, Th., F.J.Alaya, G.L.Stebbins and J.M.Valentine. Surjeet Publication, Delhi.
● Evolutionary Biology, Futuyamma, D.J.Sinauer Associates, INC Publishers, Sunderland.
● Evolution, Hall, B. K. and Hallgrimsson, James and Bartlett Publisher, Sudbury, USA. 48
● Evolutionary Genetics. Smith,J.M. Oxford University Press, New York. ∙ Evolution. Strikberger,
● M.W.Jones and Barlett Publishers, Boston London chordates
e-CONTENT:
● https://archive.nptel.ac.in/courses/102/104/102104056/
● NPTEL https://nptel.ac.in/courses/103101127
● epg pathshala
● https://epgp.inflibnet.ac.in/Home/ViewSubject?ca tid=2rAs1Puvga4LW93zMe83aA ==∙ https://www.swayamprabha.gov.in/index.php/program/current_he/9
e- JOURNAL:
● Journal of Evolutionary Biology Evolution and Human behaviour Nature Ecology and Evolution