GENETICS AND EVOLUTIONARY BIOLOGY (Theory)

Paper Code: 
25CZOL401
Credits: 
4
Contact Hours: 
4.00
Max. Marks: 
100.00
Objective: 

Course objectives:

This course will enable the students to -

1.    Develop detailed knowledge of Mendelian inheritance and interactions of Genes

2.    Analyze crossing over and linkage in heredity and chromosome mapping.

3.    Perceive the concept of sex determination.

4.    Acquire the knowledge about origin of life and concept of speciation

Course Outcomes: 

Course

Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Course Code

Course Title

25CZOL

401

GENETICS AND

EVOLUTIONARY BIOLOGY

CO 37:  Outline  detailed

knowledge      about                      the

patterns     of                 Mendelian

inheritance and

interactions of Genes and

their expressions.

CO 38: Compare the role

of     crossing     over       and

linkage    in  heredity              and

acquire knowledge about sex linked inheritance, cytoplasmic inheritance and polygenic inheritance.

CO       39:Perceive           the

concept    of mutation and sex determination

CO 40: Acquire knowledge

on   evolutionary       theories

and evidences of evolution

and process of evolutionary

change

CO 41: Build the concept

of                             Natural

selection,speciation                                  and

macroevolution

CO42:Contribute

effectively       in                     course-

specific interaction

The    approach

in teaching:

Interactive

Lectures,

Discussion,

Tutorials,

Reading

assignments,

Demonstration,

Team     teaching

Learning

activities for the         students:

Self-learning

assignments,

Effective

questions,

Simulation,

Seminar

presentation,

Giving        tasks,

Chart

preparation

Assessment

Strategies

Class test,

Semester end

examinations,

Quiz, Solving

problems in

tutorials,

Assignments,

Presentation.

 

12.00
Unit I: 
Introduction to Genetics - I

Introduction to Genetics: Mendel’s work on transmission of traits

Mendelian Genetics and its Extension: Principles of Inheritance, Chromosome theory of inheritance, Incomplete dominance and codominance, Multiple alleles, Lethal alleles, Epistasis, Pleiotropy

12.00
Unit II: 
Introduction to Genetics - II

Sex linked inheritance, extra-chromosomal inheritance, Polygenic inheritance, Linkage, Crossing Over, Recombination frequency as a measure of linkage intensity

12.00
Unit III: 
Introduction to Genetics - III

Mutations - Chromosomal Mutations: Deletion, Duplication, Inversion, Translocation, Aneuploidy and Polyploidy

Gene mutations: Induced versus Spontaneous mutations, Back versus Suppressor mutations

Sex Determination: Environmental sex determination  & Chromosomal mechanisms

12.00
Unit IV: 
Introduction to Evolutionary Theories

Lamarckism, Darwinism, Neo-Darwinism

Direct Evidences of Evolution: Types of fossils, Incompleteness of fossil record Processes of Evolutionary Change: Organic variations

Isolating Mechanisms

12.00
Unit V: 
Introduction to Evolutionary process

Natural selection (Example: Industrial melanism); Artificial selection

Species Concept: Biological species concept (Advantages and Limitations); Modes of speciation (Allopatric, Sympatric)

Macro-evolution: Macro-evolutionary Principles (example: Darwin’s Finches)

Essential Readings: 

ESSENTIAL READINGS:

●     Gardner, E.J., Simmons, M.J., Snustad, D.P. (2008). Principles of Genetics. VIII Edition. Wiley India.

●     Snustad, D.P., Simmons, M.J. (2009). Principles of Genetics. V Edition. John Wiley and Sons Inc.

●     Genetics; Winchester, A.M; Oxford and IBH Publishing Co.

●     Genetics; Strickberger; Macmillan, Prentice Hall of India.

●     Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.

●     Primrose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation,  WilleyBlacwell.

●     BenjaminCummings Russell, P. J. (2009). Genetics- A Molecular Approach.III Edition. ∙ BenjaminCummings Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C. and Carroll, S.B. Introduction to Genetic Analysis. IX Edition.

●     Evolution, V.B.Rastogi, Kedar Nath, Ram Nath, Merrut. Genes and Evolution. JhaA.P John Publication, New Delhi

References: 

SUGGESTED READINGS:

●     Klug, W.S., Cummings, M.R., Spencer, C.A. (2012). Concepts of Genetics. X Edition. Benjamin Cummings.

●     Russell, P. J. (2009). Genetics- A Molecular Approach. III Edition. Benjamin Cummings.

●     Griffiths, A.J.F., Wessler, S.R., Lewontin, R.C. and Carroll, S.B. Introduction to Genetic Analysis. IX Edition.

●     W. H. Freeman and Co. Ridley, M. (2004). Evolution. III Edition. Blackwell Publishing ∙ Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B. and Patel, N. H. (2007). Evolution. Cold Spring, Harbour Laboratory Press.

●     Hall, B. K. and Hallgrimsson, B. (2008). Evolution. IV Edition. Jones and Bartlett Publishers

●     W. H. Freeman and Co. Ridley, M. (2004). Evolution. III Edition. Blackwell Publishing ∙ Barton, N. H., Briggs, D. E. G., Eisen, J. A., Goldstein, D. B. and Patel, N. H. (2007). Evolution. Cold Spring, Harbour Laboratory Press.

●     Hall, B. K. and Hallgrimsson, B. (2008). Evolution. IV Edition. Jones and Bartlett Publishers

●     Campbell, N. A. and Reece J. B. (2011). Biology. IX Edition, Pearson, Benjamin, Cummings.

●     Genetics and Origin of Species. Dobzhansky, Th., F.J.Alaya, G.L.Stebbins and J.M.Valentine. Surjeet Publication, Delhi.

●     Evolutionary Biology, Futuyamma, D.J.Sinauer Associates, INC Publishers, Sunderland.

●     Evolution, Hall, B. K. and Hallgrimsson, James and Bartlett Publisher, Sudbury, USA. 48

●     Evolutionary  Genetics. Smith,J.M. Oxford University Press, New York.                  ∙ Evolution. Strikberger,

●     M.W.Jones and Barlett Publishers, Boston London chordates

e-CONTENT:

●     https://archive.nptel.ac.in/courses/102/104/102104056/

●     NPTEL https://nptel.ac.in/courses/103101127

●     epg pathshala

●     https://epgp.inflibnet.ac.in/Home/ViewSubject?ca tid=2rAs1Puvga4LW93zMe83aA ==∙ https://www.swayamprabha.gov.in/index.php/program/current_he/9

e- JOURNAL:

●     Journal of Evolutionary Biology Evolution and Human behaviour Nature Ecology and Evolution

Academic Year: