Coming soon
Genetics and Biostatistics
Course objectives:
This course will enable the students to –
- Analyze the patterns of Mendelian inheritance and Interactions of Genes and their expressions.
- Appraise role of crossing over and linkage in heredity
- Examine cytoplasmic inheritance and its importance.
- Implement the role of genetics in human welfare and genetic counseling.
- Test how natural polymorphism and genetic variation can give rise to mutant genes, and how these genetic errors are inherited;
- Execute the scope and application of Biostatistics and Use of data analysis methods.
Course Outcomes (COs):
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL-214 |
Genetics & Biostatistics |
The students will : CO 36: Examine the patterns of Mendelian inheritance and Interactions of Genes and their expressions. CO 37: Interpret the role of crossing over and linkage in heredity. Describe cytoplasmic inheritance and its importance. CO 38: Implement the role of genetics in human welfare and genetic counseling. CO 39: Argue how natural polymorphism and genetic variation can give rise to mutant genes, and how these genetic errors are inherited;
CO 40: Appraise the scope and application of Biostatistics and implement the data analysis methods in the field of research. |
The approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration,
Learning activities for the students: Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks,
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Class test Semester end examinations, Quiz, Assignments, Presentation Surprise test Open book test
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- Mendelian inheritance patterns & laws of heredity
- Co and incomplete dominance
- Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)
- Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh
- Gene expression- Lethal genes, Pleiotropic genes
- Multiple genes- Seed coat in wheat, skin colour in human
● Linkage & construction of linkage maps
● Crossing over- Mechanism, theories, Cytological detection & significance
● Cytoplasmic inheritance
● Human genetics- Chromosomal & single gene disorder, Genetics counseling, Amniocentesis
Eugenics & Euthenics
- Determination of Sex – Chromosomal mechanism & environmental influence, the sexual function of X &Y chromosome, Gyandromorphs, Genic Balance Theory,
- Sex linked inheritance in man & Drosophila, Y linked genes, Sex limited genes, Sex influenced genes
- Mutations- Chromosomal aberrations, Gene mutations
- Introduction, scope and application of Biostatistics
- Frequency distribution
- Graphical presentation of data (bar diagram, frequency polygon, histogram, pie chart)
- Mean. mode, median and their significance
- Standard deviation ,variance and coefficient of variance
- Tests of significance- t-test(1 population & 2 population test), Chi-square( independence of attributes)
- A Textbook of Genetics; Rastogi, V.B.; Ramnath&Kedarnath.
- Genetics: Gupta P.k.; Rastogi publication.
- Cell and Molecular Biology; Phillip Sheeler, Donald E. Bianchi; John Wiley and Sons.
- Biostatistics; Gupta, S.P.;Sultan Chand &Co.
- Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
- Genetics; Strickberger; Macmillan, Prentice Hall of India.
- Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
- Primose, S.B. Tyman, R.M. and Old, R.W. Principles of gene manipulation, Willey- Blacwell.
- Cell and Molecular Biology; Gerald Karcp; John Wiley and Sons,inc
- A Textbook of Genetics; Rastogi, V.B.; Ramnath&Kedarnath.
- Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings
- Bencroft, H. Introduction to Biostatistics Harper and Row. New York, 1957.
- Bailey, N.T.J. Statistical method in Biology Low Priced Text Book English Language Society, London, 1959.
- Bishop O.N. Statistics for biology, Prentice Hall Press
- Mahajan B.K., Methods in Biostatistics, Jaypee.
