ENVIRONMENTAL TOXICOLOGY I

Paper Code: 
24ZOL323C
Credits: 
4
Contact Hours: 
4.00
Max. Marks: 
100.00
Objective: 
Course objectives:
This course will enable the students to –
1. Analyze detailed understanding of different branches of toxicology
2. Educated about toxicants present in nature and their effect on the environment and living organisms.
 
Course Outcomes: 

Course

Learning outcomes (at course level)

Learning and teaching strategies

Assessment Strategies

Course Code

Course Title

 

 

 

 

 

 

 

 

 

 

24ZOL

323C

 

 

 

 

 

 

 

 

 

 

Environmental Toxicology I

(Theory)

CO97. List the different                    branches and

principles of Toxicology CO98. Explain

mechanism     of                       toxic agents

CO99. Analysis of Specific    response                of toxicity.

CO100. Evaluate target organ toxicity

CO101.                         Discover physicochemical

nature of toxicants and effect of toxic agents CO102.                       Contribute effectively   in                    course- specific interaction

Approach in teaching: Interactive Lectures, Reading assignments,

 

Learning activities for the students: Effective questions, Simulation,

Seminar presentation,

Class test Semester                 end examination, Viva

 

10.00
Unit I: 
UNIT I
• History and Scope of Toxicology Principles of Toxicology
● Different Areas of Toxicology
● Classification of Toxic Agent
● Spectrum of Undesired Effects Interaction of Chemicals
● Additive
● Synergistics
● Potentiation
● Antagonism Dose Response Individual or Graded
● Response Relationships
 
● Quantal Dose
● Dose Response Curves Variation in Toxic Responses
● Selective Toxicity
● Species Differences
● Individual Differences Animal Toxicity Tests
● Acute
● Subacute
● Sub chronic
● Chronic
● Development and Reproductive Toxicology
● Mutagenicity
● Skin and Eye Irritation
 
15.00
Unit II: 
Unit II
• Mechanisms of Toxicity
● Delivery
● Absorption
● Distribution
● Excretion
● Cellular Dysfunctions and result and toxicities
● Repair or Dysrepair Biotransformation of Xenobiotics
● Phase I Enzymes (Hydrolysis, Reduction,Oxidation
● Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acetylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation) Risk Assessment
● Hazard Identifications (Assessing Toxicity Of Chemicals)
● Risk Characterization
● Risk Perception & comparative Analysis of Risk
● Environmental Impact Assessment
 
10.00
Unit III: 
Unit III
Specific Responses of Toxicity
● Carcinogenesis
● Mutagenicity (Genetic Toxicology)
● Teratogenicity (Development Toxicity)
 
15.00
Unit IV: 
Unit IV
Target Organ Toxicity
● Liver
● Kidney
● Nervous System
● Blood
 
10.00
Unit V: 
Unit V
• Physicochemical nature & Effect of Toxic Agents
● Pesticides: (General account) Organochlorine Compound, Anticholinesterase agents and Pyrethroids esters
● Metals (Arsenic, Lead, Mercury)
● Industrial Solvents (General Account)
● Radiation & Radioactive Materials
 
Academic Year: 
2024-2025
  • Printer-friendly version
  • PDF version