Environmental Toxicology I

Paper Code: 
ZOL 323 C
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
10.00
Unit I: 
Unit I

History and Scope of Toxicology

Principles of Toxicology

  • Different Areas of Toxicology
  • Classification of Toxic Agent
  • Spectrum of Undesired Effects

Interaction of Chemicals

  • Additive
  • Synergistics
  • Potentiation
  • Antagonism

Dose Response

  • Individual or Graded
  • Response Relationships
  • Quantal Dose
  • Dose Response Curves

Variation in Toxic Responses

  • Selective Toxicity
  • Species Differences
  • Individual Differences

Animal Toxicity Tests

  • Acute
  • Subacute
  • Subchronic
  • Chronic
  • Development and Reproductive Toxicology
  • Mutagenicity
  • Skin and Eye Irritation
15.00
Unit II: 
Unit II

Mechanisms of Toxicity

  • Delivery
  • Absorption
  • Distribution
  • Excretion
  • Cellular Dysfunctions and resultant toxicities
  • Repair or Dysrepair

Biotransformation of Xenobiotics

  • Phase I Enzymes (Hydrolysis, Reduction, Oxidation
  • Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acelylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation)

Risk Assessment

  • Hazard Identifications (Assessing Toxicity of Chemicals)
  • Risk Characterization
  • Risk Perception & comparative Analysis of Risk
  • Environmental Impact Assessment
10.00
Unit III: 
Unit III

Specific Responses of Toxicity

  • Carcionogenesis
  • Mutagenecity (Genetic Toxicology)
  • Teratogenecity (Development Toxicity)
15.00
Unit IV: 
Unit IV

Target Organ Toxicity

  • Liver
  • Kidney
  • Nervous System
  • Blood
     
Unit V: 
Unit V

Physicochemical nature & Effect of Toxic Agents

  • Pesticides: (General account ) Organochlorine Compound, Antocholinesterase agents and pyrethroids esters
  • Metals (Arsenic,Lead, Mercury)
  • Industrial Solvents (General account)
  • Radiation & Radioactive materials
Academic Year: 
2016-2017
  • Printer-friendly version
  • PDF version