Environmental Toxicology I

Paper Code: 
ZOL 323 C
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 
Course objectives:
 
This course will enable the students to –
 
  1. Analyse  detailed  understanding of different branches of toxicology
  2. Enlighten about toxicants present in nature and their effect on the environment and living organisms.
Course Outcomes (COs):
 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 323C

Environmental Toxicology I

 

Students will –

CO82: Describe different branches of toxicology

CO83: Analyse Toxicant present in the nature and their effect on environment and living organisms

CO84 : Explain about types of Toxicity

CO85: Perceive principles of Toxicology

CO86: Discover mechanism,  Physicochemical nature of Toxicants and Effect of Toxic Agents

 

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching

 

Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

 

Class test

Semester end examinations,

Viva

 

10.00
Unit I: 
UNIT I :
  • History and Scope of Toxicology Principles of Toxicology
  • Different Areas of Toxicology
  • Classification of Toxic Agent
  • Spectrum of Undesired Effects Interaction of Chemicals
  • Additive
  • Synergistics
  • Potentiation
  • Antagonism Dose Response
  • Individual or Graded
  • Response Relationships
  • Quantal Dose
  • Dose Response Curves Variation in Toxic Responses
  • Selective Toxicity
  • Species Differences
  • Individual Differences Animal Toxicity Tests
  • Acute
  • Subacute
  • Subchronic
  • Chronic
  • Development and Reproductive Toxicology
  • Mutagenicity
  • Skin and Eye Irritation
15.00
Unit II: 
UNIT II :
  • Mechanisms of Toxicity
  • Delivery
  • Absorption
  • Distribution
  • Excretion
  • Cellular Dysfunctions and result and toxicities
  • Repair or Dysrepair Biotransformation of Xenobiotics
  • Phase I Enzymes (Hydrolysis, Reduction,Oxidation
  • Phase II Enzyme Reactions (Glucuronidation, Sulfation, Methylation, Acetylation, Amino-acid conjugation Glutathione Conjugation, Phosphorylation)
  • Risk Assessment
  • Hazard Identifications (Assessing Toxicity Of Chemicals)
  • Risk Characterization
  • Risk Perception & comparative Analysis of Risk
  • Environmental Impact Assessment
10.00
Unit III: 
UNIT III
  • Specific Responses of Toxicity
  • Carcinogenesis
  • Mutagenicity (Genetic Toxicology)
  • Teratogenicity (Development Toxicity)
15.00
Unit IV: 
UNIT IV
  • Target Organ Toxicity
  • Liver
  • Kidney
  • Nervous System
  • Blood
 
10.00
Unit V: 
UNIT V
  • Physicochemical nature & Effect of Toxic Agents
  • Pesticides: (General account )Organochlorine Compound, Anticholinesterase agents and Pyrethroids esters
  • Metals (Arsenic, Lead, Mercury)
  • Industrial Solvents(General Account)
  • Radiation &Radioactive Materials
Academic Year: 
2021-2022
  • Printer-friendly version
  • PDF version