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Embryology and Teratology
Paper Code:
LSC 144 B
Credits:
04
Contact Hours:
60.00
Max. Marks:
100.00
15.00
Unit I:
Teratogenesis
- General principle of teratology (genetic factors, critical period, initiating mechanism, consequences of abnormal development, Access to embryo and fetus- dose response relationship)
- Teratological mechanism (mutation, chromosomal abnormalities, mitotic interference, interference with nucleic acid function, nutritional deficiencies , altered energy, changes in osmolarity, changes in cell membrane, enzyme inhibition.)
- Teratogens; some specific examples.(Human and experimental animals)
- Transport and biotransformation of xenobiotics by placenta/extra embryonic membranes.
10.00
Unit II:
Reproductive Toxicology
- Female reproduction (Hypothalamus, ovary assessment of female reproductive functions),
- Male reproduction (Biology of male reproduction, assessment of male reproductive function)
10.00
Unit III:
Embryogenesis of Chick
• Reproduction
• Structure and chemistry of the fertilized egg
• Cleavage
• Blastulation
• Gastrulation
• Neurulation and tabulation
10.00
Unit IV:
Development of chick according to the hours of incubation
- 24hrs
- 33 hrs
- 48 hrs
- 72 hrs
- 96 hrs till hatching.
- Extra embryonic membranes of chick-types and their development
15.00
Unit V:
Avian Teratology
- Acute Oral Toxicity Studies
- Dietary Toxicity Studies
- Endocrine Disruptor Studies
- Embryotoxicity of Industrial Chemical on chick embryo
- Physiological and Biological effects of pesticide residues in poultry
Essential Readings:
Books Recommended:
- Developmental Biology:Scott F.Gilbert;Sinauer Associates,Inc.Publishers
- An Introduction to Embryology:B.I.Balinsky:Thomson Brooks
Academic Year:
