Developmental Biology

Paper Code: 
ZOL 413
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

Course objectives:

 

This course will enable the students to -

 

  1. Understand the mechanism of development of an individual from a single cell zygote
  2. Enlighten about the events of fertilization, types of cleavage, stages and cellular mechanisms for gastrulation.
  3. Acquaintance about fate maps, extraembryonic membranes and Organogenesis in Chick,
  4. Discussion about the types & physiology of the placenta
  5. Study about metamorphosis and the role of Hormones involved in the process.
  6. Describe the process of Apoptosis and Teratogenesis

 

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment

Strategies

Paper Code

Paper Title

ZOL-413

Developmental biology

The students will be able to

CO 69: Describe the mechanism of development of an individual from a single cell zygote

CO 70: Explain the process of fertilization, types of cleavage, stages and cellular mechanisms for gastrulation.

CO 71: Know about Organogenesis in Chick, Extra embryonic membranes, Types & physiology of the placenta

CO 72: Describe the Role of Hormones in metamorphosis

CO 73: Discuss the process of Apoptosis and Teratogenesis.

The approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations, Explanation by videos

Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks

 

Class test

Semester end examinations,

Quiz,

Assignments,

Presentation

Surprise test

Open book test

 

 

9.00
Unit I: 
UNIT I

Baer’s Law, Biogenetic Law

Gametogenesis- Spermatogenesis & Oogenesis, Vitellogenesis

Fertilization- Approximation of Gametes, Capacitation and contact, Acrosomal reactions, activation of ovum,Migration of Pronuclei and Amphimixis and Significance

10.00
Unit II: 
UNIT II

Types of eggs

Cleavage: Planes and Patterns of cleavage, Types of cleavage

Blastulation, Gastrulation, Morphogenetic Movements(Types and Significance)

Neurulation, Morphogenesis and Growth,

10.00
Unit III: 
UNIT III

Fate maps (amphibian andchick): Methods of preparation of Fate maps

Organogenesis in Chickupto 96 hours of incubation

 Extra embryonic membranes

Types & physiology of placenta

9.00
Unit IV: 
UNIT IV

Concept of Embryonic Induction (types) and Competance

Teratogenesis: Birth defects in chick

Regeneration in Vertebrates

Ageing(overview)

Stem Cells: Types and Significance

7.00
Unit V: 
UNIT V

Metamorphosis in Frog & Insects.

 Role of Hormones in metamorphosis

Parthenogenesis

Essential Readings: 

 

  • Gilbert, S. F. (2010). Developmental Biology, IX Edition, SinauerAssociates,Inc., Publishers, Sunderland, Massachusetts, USA.
  • Balinsky B. I. and Fabian B. C. (1981). An Introduction to Embryology, VEdition, International Thompson Computer Press.
  • Carlson, R. F. Patten's Foundations of Embryology
  • Kalthoff (2008). Analysis of Biological Development, II Edition, McGraw-HillPublishers.
  • Lewis Wolpert (2002). Principles of Development. II Edition, Oxford UniversityPress.
  • Developmental Biology. Berril. N.J. and Karp. G.McGraw Hill, New York.
  • Gene activity during early development, Davidson, E. H. Academic Press, New York.

 

Academic Year: 
2020-2021
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