Developmental Biology

Paper Code: 
ZOL-413
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 

 

This course will enable the students to -

  • Appraise the mechanism of development of an individual from a single cell zygote
  • Review the events of fertilization, types of cleavage, stages and cellular mechanisms for gastrulation.
  • Construct fate maps
  • Speculate the process of organogenesis in Chick,
  • Analyse the types & physiology of the placenta
  • Evaluate the role of hormones in metamorphosis. 
  • Describe the process of Teratogenesis

 

Course Outcomes (COs): 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment 

Strategies

Paper Code

Paper Title

ZOL-413

Developmental biology

The students will 

CO 69: Critically analyse the mechanism of development of an individual from a single cell zygote 

CO 70: Conjecture the process of fertilization, types of cleavage, stages and cellular mechanisms for gastrulation.

CO 71: Interpret organogenesis in Chick, Extra embryonic membranes, Types & physiology of the placenta

CO 72: Relate the Role of Hormones in metamorphosis 

CO 73: Judge the role of various  teratogens

The approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations, Explanation by videos

Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks

  • Class test 

  • Semester end examinations,

  • Quiz, 

  • Assignments, 

  • Presentation

  • Surprise test

  • Open book test

 

9.00
Unit I: 
UNIT I
 
  • Baer’s Law, Biogenetic Law
  • Gametogenesis- Spermatogenesis & Oogenesis, Vitellogenesis
  • Fertilization- Approximation of Gametes, Capacitation and contact, Acrosomal reactions, activation of ovum,Migration of Pronuclei and Amphimixis and Significance

 

10.00
Unit II: 
UNIT II
  • Types of eggs
  • Cleavage: Planes and Patterns of cleavage, Types of cleavage
  • Blastulation, Gastrulation, Morphogenetic Movements(Types and Significance)
  • Neurulation, Morphogenesis and Growth

 

10.00
Unit III: 
UNIT III
  • Fate maps (amphibian andchick): Methods of preparation of Fate maps
  • Organogenesis in Chickupto 96 hours of incubation
  • Extra embryonic membranes
  • Types & physiology of placenta
9.00
Unit IV: 
UNIT IV
  • Concept of Embryonic Induction (types) and Competance
  • Teratogenesis: Birth defects in chick
  • Regeneration in Vertebrates
  • Ageing(overview)
  • Stem Cells: Types and Significance

 

7.00
Unit V: 
UNIT V
  • Metamorphosis in Frog & Insects.
  • Role of Hormones in metamorphosis
  • Parthenogenesis

 

Essential Readings: 
  • Gilbert, S. F. (2010). Developmental Biology, IX Edition, SinauerAssociates,Inc., Publishers, Sunderland, Massachusetts, USA.
  • Balinsky B. I. and Fabian B. C. (1981). An Introduction to Embryology, VEdition, International Thompson Computer Press.
  • Carlson, R. F. Patten's Foundations of Embryology
  • Kalthoff (2008). Analysis of Biological Development, II Edition, McGraw-HillPublishers.
  • Lewis Wolpert (2002). Principles of Development. II Edition, Oxford UniversityPress.
  • Developmental Biology. Berril. N.J. and Karp. G.McGraw Hill, New York.
  • Gene activity during early development, Davidson, E. H. Academic Press, New York.
Academic Year: 
2021-2022
  • Printer-friendly version
  • PDF version