Cell Biology & Genetics I

Paper Code: 
ZOL-102
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 
Course Objectives: 
This course will enable the students to 
1. Develop an understanding of the structure and functions of basic components of  prokaryotic architecture and eukaryotic cells and their organelles. 
2. Analyzing comprehensive knowledge about an overview of cell theory, role of membrane in transport of molecules across the cell and how these cellular components are used to generate and utilize energy in cells. 
3. Distinguish between the process of cell division in somatic and germ cells. 
4. Develop understanding of Mendelian inheritance patterns & laws of heredity, Interactions of Genes and their expressions, process of crossing over and linkage in genes etc. 
 

Course Outcomes (COs):

Course

Learning outcomes 

(at course level)

Learning and 

teaching 

strategies

Assessment 

Strategies

Paper 

Code

Paper 

Title

ZOL

102

Cell Biology  &

Genetics I

The students will -

CO5: Differentiate the 

structures and purpose of  basic components of  prokaryotic and eukaryotic  cells, especially 

macromolecules, 

membranes, and organelles.  CO6: Relate the structure,  function and composition of  the plasma membrane.

CO7: Conceptualize the  importance of nucleus and its  components and process of  cell division

CO8: Judge how the  endoplasmic reticulum and  golgi apparatus interact with  one another and participate  in molecular trafficking in  the cell.

CO9: Assemble detailed  knowledge about the patterns  of Mendelian inheritance and  interactions of Genes and  their expressions.

CO10: Compare the role of  crossing over and linkage in  heredity and cytoplasmic  inheritance.

Approach in 

teaching:

Class Lectures,

Discussion, 

Tutorials, 

Reading

assignments,

Demonstration

Learning 

activities for the  students:

Self-learning

assignments,

Effective

questions,

Question

preparation,

 

 

 

 

Seminar 

presentation, 

Giving tasks.

Regular Class test  Semester end 

examinations

Quiz

Solving problems in  tutorials

Assignments

Presentation

Individual and 

group projects
 

 

 

 

 

11.00
Unit I: 
Unit I
 
● Diversity of Cell Size & shape 
● Cell theory 
● Structure of Prokaryotic & Eukaryotic cells 
● Cell membrane structure and function 
● Active and Passive transport across membranes 
● Pinocytosis, Phagocytosis, Endocytosis, Exocytosis 
12.00
Unit II: 
Unit-II
Cell organelles, their structure, composition & function 
 
● Endoplasmic reticulum 
● Golgi complex 
● Ribosome : structure & functions 
● Lysosomes: Function & intracellular digestion 
● Mitochondria: Organization &function 
● Peroxisomes 
● Centrioles & Microtubules: cilia & flagella 
8.00
Unit III: 
Unit III
Nucleus 
 
● Nucleus structure: Structure & function of nuclear envelope, nuclear matrix and nucleolus
● Cell cycle( S, G1,G2,M phase) 
● Mitosis: Phases & process of mitosis 
● Meiosis: Phases & Process of meiosis 
Unit IV: 
IV
Concepts of Genetics 
● Mendelian inheritance patterns & laws of heredity 
● Co and incomplete dominance 
● Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis (dominant &  recessive)
● Multiple alleles-Coat colour in rabbit, Human blood group-ABO 
● Gene expression- Lethal genes, Pleiotropic genes 
● Multiple genes- skin colour in human 
 

 

6.00
Unit V: 
Unit V
● Linkage & construction of linkage maps 
● Crossing over- Mechanism, theories, Cytological detection & significance 
● Cytoplasmic inheritance 
 
Essential Readings: 
ESSENTIAL READINGS:
● Cell Biology by C.B. Powar; Himalaya Publishing House. 
● Cell and Molecular Biology; Phillip Sheeler Donald E. Bianchi; John Wiley and Sons. 
● The Cell: A Molecular Approach. Cooper, G. Houseman G.R. SinaeurAssoc, New York. 
● Cell and Molecular Biology; De Robertis and De Robertis; Saunders College. 
 
SUGGESTED READINGS:
● Cell and Molecular Biology; Gerald Karp; John Wiley and Sons, inc 
● Essentials cell Biology II Ed., Bruce Alberts, Julian Lewis, James D.Watson; Garland  Publishing. 
● Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
 
e-RESOURCES:
● Cell biology -NPTEL- https://nptel.ac.in/courses/102103012
● Molecular Biology-NPTEL-https://nptel.ac.in/courses/102104052
 
e- JOURNAL:
● Molecular and Cellular Biology
● BMC Cell and Molecular Biology- ISSN: 2661-8850
Academic Year: 
2022-2023
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