Cell Biology& Genetics I

Paper Code: 
ZOL-102
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
11.00
  • Diversity of Cell Size & shape
  • Cell theory
  • Structure of Prokaryotic & Eukaryotic cells
  • Magnification , resolving power
  • Principles of microscope and application:

               Light Microscopy

               Phase contrast microscopy

               Fluorescence Microscopy

               Electron Microscopy (SEM & TEM)

Cell fractionation & Centrifugation
 
12.00

Cell organelles, their structure, composition & function

  • Endoplasmic reticulum
  • Golgi complex
  • Ribosome : structure & functions
  • Lysosomes: Function & intracellular digestion
  • Mitochondria: Organization &function, Oxidative phosphorylation and biogenesis
  • Peroxisomes
  • Centrioles & Microtubules: cilia & flagella
 
8.00



·        Active and Passive transport across membranes

·        Pinocytosis, Phagocytosis

·        Endocytosis, Exocytosis

·         Cell cycle( S, G1,G2,M phase)

·        Mitosis: Phases & process of mitosis, structure & function of spindle apparatus

·        Meiosis: Phases & Process of meiosis

Cytology of Cancer

8.00



·        Mendelian inheritance patterns & laws of heredity

·        Co and incomplete dominance

·        Interactions of Genes- Supplementary, Complementary, Duplicate, Epistasis(dominant & recessive)

·        Multiple alleles-Coat colour in rabbit, Human blood group-ABO & Rh

·        Gene expression- Lethal genes, Pleiotropic genes

·        Multiple genes- Seed coat in wheat, skin colour in human

 

 

6.00
  • Linkage & linkage maps
  • Crossing over- Mechanism, theories, Cytological detection & significance
  • Cytoplasmic inheritance
 

 

Essential Readings: 
  • Cell Biology and Genetics; Kohli, K.S;Ramesh Book Depot
     Genetics; Winchester, A.M; Oxford and IBH Publishing Co.
  • Cell and Molecular Biology; De Robertis and De Robertis; Saunders College.
  • Genetics; Strickberger; Macmillan, Prentice Hall of India.
  • Cell Biology; Powar, C.B;  Himalayan publishing House.
  • Principles of Genetics; Gardener, E,J; Wiley eastern, New Delhi.
  • A Textbook of Genetics; Rastogi, V.B.; Ramnath & Kedarnath.
  • Cell and Molecular Biology; Gerald Karp; John Wiley and Sons,inc
  • Molecular Biology of the cell; Bruce Alberts, Julian Lewis, James D.Watson; Garland Publishings   
  • Cell and Molecular Biology; Phillip Sheeler   Donald E. Bianchi; John Wiley and Sons.
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