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Admissions

It is a University which is committed to excellence and overall development of the student and one where talent is nurtured and honed in the best possible manner. Come, be a part of our never-ending journey of accomplishments and accolades.

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Placements

Excellent education not only imparts knowledge, but also paves the way for a promising and successful career. The Placement Cell at The IIS University has numerous success stories to narrate in this regard...

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Life@IIS Univ

Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with vibrant events and memorable occasions to cherish for a lifetime.

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Academics

Taking the age-old tradition of enlightenment through education forward, The IIS University - in its continuous pursuit of excellence - firmly believes that an institution’s academic profile determines its worth and value. Therefore, on offer are a wide variety of both conventional and contemporary programmes of study.

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Research

To stimulate curiosity and cater to the global needs of a dynamic education, The IIS University - since inception - has been promoting and encouraging research-based experiential learning among all its students.

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About Us

The IIS University, with its perfect amalgamation of innovation, inspiration and synergy, aims to be a model institution for students across disciplines and programmes.

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IIS Univ
  • Admissions

    It is a University which is committed to excellence and overall development of the student...

  • Placements

    Excellent education not only imparts knowledge, but also paves the way for...

  • Life@IIS Univ

    Life @ IISU is nothing less than a kaleidoscope of myriad hues; complete with...

  • Academics

    Taking the age-old tradition of enlightenment through education forward,...

  • Research

    To stimulate curiosity and cater to the global needs of a dynamic education,...

  • About Us

    The IIS University, with its perfect amalgamation of innovation, inspiration...

IIS (Deemed to be University)

Gurukul Marg, SFS, Mansarovar, Jaipur 302020, (Raj.) India

Phone:- +91-141-2400160-61, 2397906-07,

Fax: 2395494,2781158, Toll Free No.: 1800 180 7750

Cell Biology | Zoology

Cell Biology

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Paper Code: 
ZOL 122
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course objectives:

This course will enable the students to –

  1. Formulate basic concepts of cellular structure and function covering all the components of prokaryotic and eukaryotic cells, especially macromolecules, membranes, and organelles.
  2. Investigate an account of the complex regulatory mechanisms that control cell functions therefore it will help students to understand how these cellular components are used to generate and utilize energy in cells.

 

Course Outcomes (COs):

tab

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 122

 

Cell Biology

The students will-

 

CO6: Analyse the functions of nucleus and extra nuclear organelles and understand the intricate cellular mechanisms involved.

CO7: Appraise the detailed knowledge of different pathways related to cell signalling and apoptosis thus enabling them to understand the anomalies in cancer

CO8:Develop an understanding about how cells work in healthy and diseased states and to give a ‘health forecast’ by analyzing the genetic database and cell information.

CO9: Investigate new avenues of joining research in areas such as genetic engineering of cells, cloning, vaccines development, human fertility programme, organ transplant, etc.

CO10: Develop an understanding how tissues are produced from cells in a normal course and about any malfunction which may lead to benign or malignant tumor.

CO11: Differentiate and evaluate the role of different cytoskeleton components in intracellular movements and intercellular interactions.

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations

 

Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks.

Class test

Semester end examinations,

 Quiz,

Assignments,

Presentation

Open book test

 

 

9.00
Unit I: 
UNIT I
  • Cell Theory
  • Structure of prokaryotic and eukaryotic cells.
  • Cell organelles-ER, Golgi, Mitochondria, Ribosomes, Peroxisomes
  • Cytoskeleton: Structure, Function and Dynamics of

      Microfilaments: Actin and Myosin

 Microtubule in mitosis.

 Kinesin and Dynein.

 Intermediate Filaments

 

 

9.00
Unit II: 
UNIT II

Bio membranes

  •   Phospholipids: main lipid constituent.
  •   Cytosolic and exoplasmic face of bio membranes.
  •   Intrinsic and extrinsic proteins.
  •  Glycolipids.
  •  Mobility of lipids and integral proteins
  •   Fluidity of bio membrane.

 Transport across cell membranes.

  • Passive Transport
  • Diffusion & Facilitated Diffusion
  •  Osmosis and water channels.
  •   Active Transport- pumps, ABC transporters
  • Cotransport by symporters and antiporters

 

15.00
Unit III: 
UNIT III
Cell-Cell Signalling.
  • Endocrine, paracrine, autocrine signalling.
  •  Receptor Proteins- Intracellular Receptors.
  • Cell surface receptors-G-protein coupled receptors, ion channel receptors, tyrosine kinase linked receptors and receptors with intrinsic enzymatic acti       Second messenger system-cAMP, IP3-DAG and MAP kinase pathways.
  • Signal-Mediated transport through Nuclear Pore.
  • Nuclear Pore Complex.
  • Nuclear export signals.
  • Nuclear localization signals
 
12.00
Unit IV: 
UNIT IV
Cell Junctions: Occluding, Adherence and communicating junctions 
Cell- cell adhesion molecules
●       Selectin
●       Cadherin
●       Integrin
●       Ig Superfamily
Cell matrix adhesion
●       Integrins
●       Collagen
Non-collagen components of extracellular matrix
 
15.00
Unit V: 
UNIT V
Protein sorting and transport
● Protein secretion- Regulative and Secretory Pathways
● Targeting proteins to Endoplasmic Reticulum
● Insertion of protein into ER membrane
● Protein folding and processing in ER
● Export of proteins from ER
● cargo selection, coat protein and vesicle budding
● Post translational modification in Golgi
● Protein sorting and export from Golgi
 
Essential Readings: 
● IWASA, J., MARSHALL, W. F., & KARP, G. (2016). Karp's cell and molecular biology: concepts and experiments.
● COOPER, G. M., & HAUSMAN, R. E. (2009). The cell: a molecular approach. Washington, D.C., ASM Press.
● Nelson et al, Lehninger’s Principles of Biochemistry, 4th Edition, McMillan, 2006.
● Alberts et al, Molecular Biology of The Cell, 2nd Edition , Garland 2007.
● Lewin, Genes IX, 9th Edition , Jones & Bartlett, 2007
● Molecular Biology of the Cell ; Lewis and Watson
● Genes VII : Benjamin Lewin
● Lewis, Human Genetics, 7th Edition, WCB & McGraw, 2007.
 
 
SUGGESTED READINGS:
● Pastemak, An Introduction to Molecular Human Genetics, 2nd Edition, Fritzgarald, 2005.
● Strachen and Read, Human Molecular Genetics, 3rd Edition, Garland Sci. Publishing, 2004.
● Structural Chemistry and Molecular Biology Alexander Rich and Norman Davidson
● The Chemical Foundations of Molecular :James D. Watson
● Human Cytogenetic Techniques and Clinical Applications HemaPurandare and Arnit Chakravarty
● Progress in Nucleic Acid Research and Molecular Biology Vol. 9 J. N. Davidson
● Essentials of Human Genetics Bhatnagar,Kothari,Mehta
● Principles and Practice of Medical Genetics, by Emery, A.E.H and D.L. Rimoin (Eds_ (1990-2nd edition) Churchill Livingstone, Edinburgh.
● Molecular Basis of Inherited Diseases, (6th Edition-1989) by Scriver, C.R. A.L. Beudit, W.S. Sty ab nd D. Valle (Eds0 McGrawHill, New York.
● Human Genetics by S.D. Gangane (2nd edition-Reprint 2001), B.L Churchill Livingstone Pvt. Ltd., New Delhi.
● Genetics in Medicine by M.W. Thompson et al, 5th Edition, W.B. Sounders Company, London
● Genetic basis of common diseases by R. A. King et al, Oxford University Press.
● Mendelian inheritance in Man by Mc. Kusick V.A. (1998), 12th Edition, John Hopsins University Press, Baltimore.
 
e- RESOURCES:
● Cell biology -NPTEL- https://nptel.ac.in/courses/102103012
● Molecular Biology-NPTEL-https://nptel.ac.in/courses/102104052
 
e- JOURNAL: 
● Molecular and Cellular Biology
● BMC Cell and Molecular Biology- ISSN: 2661-8850
 
Academic Year: 
2022-2023
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