Coming soon
Cell Biology
Course objectives:
This course will enable the students to –
- Formulate basic concepts of cellular structure and function covering all the components of prokaryotic and eukaryotic cells, especially macromolecules, membranes, and organelles.
- Investigate an account of the complex regulatory mechanisms that control cell functions therefore it will help students to understand how these cellular components are used to generate and utilize energy in cells.
Course Outcomes (COs):
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL 122
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Cell Biology |
The students will-
CO6: Analyse the functions of nucleus and extra nuclear organelles and understand the intricate cellular mechanisms involved. CO7: Appraise the detailed knowledge of different pathways related to cell signalling and apoptosis thus enabling them to understand the anomalies in cancer CO8:Develop an understanding about how cells work in healthy and diseased states and to give a ‘health forecast’ by analyzing the genetic database and cell information. CO9: Investigate new avenues of joining research in areas such as genetic engineering of cells, cloning, vaccines development, human fertility programme, organ transplant, etc. CO10: Develop an understanding how tissues are produced from cells in a normal course and about any malfunction which may lead to benign or malignant tumor. CO11: Differentiate and evaluate the role of different cytoskeleton components in intracellular movements and intercellular interactions. |
Approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations
Learning activities for the students: Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks. |
Class test Semester end examinations, Quiz, Assignments, Presentation Open book test |
- Cell Theory
- Structure of prokaryotic and eukaryotic cells.
- Cell organelles-ER, Golgi, Mitochondria, Ribosomes, Peroxisomes
- Cytoskeleton: Structure, Function and Dynamics of
Microfilaments: Actin and Myosin
Microtubule in mitosis.
Kinesin and Dynein.
Intermediate Filaments
Bio membranes
- Phospholipids: main lipid constituent.
- Cytosolic and exoplasmic face of bio membranes.
- Intrinsic and extrinsic proteins.
- Glycolipids.
- Mobility of lipids and integral proteins
- Fluidity of bio membrane.
Transport across cell membranes.
- Passive Transport
- Diffusion & Facilitated Diffusion
- Osmosis and water channels.
- Active Transport- pumps, ABC transporters
- Cotransport by symporters and antiporters
- Endocrine, paracrine, autocrine signalling.
- Receptor Proteins- Intracellular Receptors.
- Cell surface receptors-G-protein coupled receptors, ion channel receptors, tyrosine kinase linked receptors and receptors with intrinsic enzymatic acti Second messenger system-cAMP, IP3-DAG and MAP kinase pathways.
- Signal-Mediated transport through Nuclear Pore.
- Nuclear Pore Complex.
- Nuclear export signals.
- Nuclear localization signals
