Cell Biology

Paper Code: 
ZOL 122
Contact Hours: 
Max. Marks: 
Course objectives:
This course will enable the students to –
  1. Formulate basic concepts of cellular structure and function covering all the components of prokaryotic and eukaryotic cells, especially macromolecules, membranes, and organelles.
  2. Investigate an account of the complex regulatory mechanisms that control cell functions therefore it will help students to  understand how these cellular components are used to generate and utilize energy in cells.
Course Outcomes (COs):


Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 122


Cell Biology

The students will-


CO6: Analyse the functions of nucleus and extra nuclear organelles and understand the intricate cellular mechanisms involved.


CO7: Appraise the detailed knowledge of different pathways related to cell signalling and apoptosis thus enabling them to understand the anomalies in cancer


CO8: Develop an understanding about how cells work in healthy and diseased states and to give a ‘health forecast’ by analyzing the genetic database and cell information.


CO9: Investigate new avenues of joining research in areas such as genetic engineering of cells, cloning, vaccines development, human fertility programme, organ transplant, etc.


CO10: Develop an understanding how tissues are produced from cells in a normal course and about any malfunction which may lead to benign or malignant tumor.


CO11: Differentiate and evaluate the role of different cytoskeleton components in intracellular movements and intercellular interactions.



Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, PowerPoint presentations


Learning activities for the students:

Self learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks.

Class test

Semester end examinations,




Open book test

Unit I: 
  • Cell Theory
  • Structure of prokaryotic and eukaryotic cells. Bio-membranes
  • Molecular composition and function.
  • Transport across cell membrane: diffusion, active transport and pumps.
  • Co-transport by symporters or antiporters
Unit II: 
  • Cytoskeleton
  • Microfilaments, Intermediate filaments and Microtubules- structure and dynamics
  • Cell movements-Intracellular transport, role of kinesin and dynein
Unit III: 

Cell –Cell Signaling and Cell Interaction

  • Introduction
  • Cell surface receptors(G-Protein coupled receptor, RTK, Cytokine receptor)
  • Second messenger system(c-AMP, PIP2,calcium)
  • MAP kinase pathways Cell junctions

Cell adhesion

Unit IV: 
Cell cycle
  • Cyclin and cyclin dependent kinases
  • Regulation of CDK – cyclin activity Chromosomes, Chromatin, and the Nucleosomes
Chromosome sequence and diversity
Unit V: 

Intracellular protein traffic

  • Uptake into ER
  • Post translational modifications
  • Golgi sorting


  • Definition ,mechanism and significance
Essential Readings: 
  • Molecular Cell Biology, J. Darnell H.Lodish and D. Baltimore Scientific American Books, Inc., USA.
  • The cell. A Molecular Approach, (4th edition), G H Cooper and R E Hausman, ASM Press, 2007.
  • Molecular and Cell Biology: concepts and experiments, (6th edition) Gerald Karp and Nancy L Pruitt
  • Cell and Molecular Biology; De Robertis and De Robertis; Saunders College
  • Cell Biology; Powar, C.B.; Himalaya Publications.
  • Molecular Biology of the gene; Watson J.D; Benjamin/ Cummings
  • Molecular Biology of the Gene. I.D Watson, N.H. Hopkins, J.W. Roberts, J.A. Steiz and AM Weiner The Benjamin/Cummings Pub. Co., Inc., California.
  • Gene IV, Benjamin Lewin. Oxford University Press, UK.
  • Molecular Biology and Biotechnology. A comprehensive desk reference, R.A.Meyers (Ed.), VCH Publishers, Inc., New York.
Academic Year: