Cell Biology

Paper Code: 
ZOL 122
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
9.00
Unit I: 
UNIT I

Cell Theory

Structure of prokaryotic and eukaryotic cells.

Bio-membranes

  • Molecular composition and function
  • Transport across cell membrane: diffusion, active transport and pumps.
  • Co-transport by symporters or antiporters

 

9.00
Unit II: 
UNIT II

Cytoskeleton

  •     Microfilaments, intermediate  filaments and microtubules-  structure and dynamics
  •     Cell movements-Intracellular transport, role of kinesin and dynein

 

15.00
Unit III: 
UNIT III

Cell –Cell Signaling and Cell Interaction

·         Introduction

·         Cell surface receptors

·         Second messenger system

·         MDP kinase pathways

 

Cell junctions

Cell adhesion

15.00
Unit IV: 
UNIT IV

Cell cycle

  • Cyclin and cyclin dependent kinases
  • Regulation of CDK – cyclin activity

Chromosomes, Chromatin, and the Nucleosomes

·        Chromosome sequence and diversity

Nucleosomes

12.00
Unit V: 
UNIT V

Intracellular protein traffic

  • Protein synthesis
  • Uptake into ER
  • Membrane proteins, Golgi sorting, Post translational modifications

Apoptosis

Definition ,mechanism and significance

Essential Readings: 

ü  Cell and Molecular Biology; De Robertis and De Robertis; Saunders College

ü  Cell Biology;  Powar, C.B.; Himalaya Publications.

ü  Molecular Biology of the gene; Watson J.D; Benzamin/ Cummings

ü  Molecular Biology of the Gene. I.D Watson, N.H. Hopkins, J.W. Roberts, J.A. Steiz and AM Weiner The Benjamin/Cummings Pub. Co., Inc., California.

ü  Molecular Cell Biology, J. Darnell H.Lodish and D. Baltimore Scientific American Books, Inc., USA.

ü  Molecular Biology of the cell. B.Alberts, D.D.Bray, J.Lewis, M.Rafif, K. Roberts and J.D.Watson. Garland Publishing inc., New York.

ü  Gene IV, Benjamin Lewin. Oxford University Press, UK.

ü  Molecular Biology and Biotechnology. A comprehensive desk reference, R.A.Meyers (Ed.), VCH Publishers, Inc., New York.

ü  Molecular Cloning: A Laboratory Manual, J.Sambrook, E.F.Fristsch and T. Maniatis, Cold Spring Harbor Laboratory Press, New York.

ü  Introduction to Practical Molecular Biology, P.D.Dabre, John Wiley& Sons Ltd. New York.

Molecular Biology Lab Fax, T.A.Brown (Ed.), Bios Scientific Publishers Ltd., Oxford. 

Academic Year: