Cancer And Radiation Biology II

Paper Code:

ZOL 423A

12.00

Unit I:

Causation of cancer :

Hereditary cancer
Virus and cancer
Chemical carcinogenesis
Hormones and cancer
Nutrition and cancer
Radiation carcinogenesis: Basic concept of free radicals and their role in cancer

12.00

Unit II:

Therapy of cancer.

Surgical removal.
Chemotherapy
Radiotherapy.
Immunotherapy.
Hyperthermia.
Management of therapy of cancer.

Prevention of cancer.

Primary prevention : Education, motivation, legislation.
Secondary prevention.
1. Detection of precancerous and early cancerous lesions
2. Chemoprevention.

12.00

Unit III:

Acute radiation effects.

Concept of LD50.
Central nervous system syndrome.
Gastro-intestinal syndrome.
Bone.marrow syndrome.
Skin reactions.

12.00

Unit IV:

Delayed effects of Radiation.

Stochastic and deterministic effects.
Radiologic aging,
Life shortening.
Radiation carcinogenesis.

12.00

Unit V:

Radiation safety and regulator aspects.

Radiographic installations.
Enclosed installations.
Field installations.
Personnel management.
Source storage facilities.
Safe work practice.
Re-commendations of National/ lnternational statutory bodies

Essential Readings:

Ramesha Rao. : Who runs the risk of cancer. Shipra Publication.
Alberts. B. Bras D. lenis J. : Molecular Biology of the cells. Govland
Publishing New York.
Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B. Lippincott.
Hall. E. J. Radiobiology for the radiobiologists. Lippincott. Philadelphia.
P.S. Lotran. V. Kumar. T.collins. : Pathology of Diseases Robbins.
Peekham. M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of
oncology Vol. I.. Vol. II. Oxford Medical Publication. Oxford University
Press. Inc. New York 1995.
Tannode. 1 F and Richand P. : The Basic science of oncology. Th II.
MacGraw-Hill
Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology.
Thomson press Ltd.. NOIDA. 1999.
Weiss. L. : Principles of metastases. Acdemic press.

Academic Year: