CANCER AND RADIATION BIOLOGY II (Practical)

Paper Code: 
25ZOL424 A
Objective: 
This course will enable the students to –
1. Develop an understanding of histopathology, histochemistry and biochemistry of various tissues after radiation treatment.
2. Differentiate and evaluate familiarity with LD50/30 in mice.
Course Outcomes: 

Course

Learning outcomes (at course level)

Learning and teaching strategies

Assessme nt

Strategie s

Course Code

Course Title

25ZOL

424A

Cancer

and

radiation biology II

(Practical)

CO186. Develop an

understanding of

histopathology,

histochemistry

of various

tissues after radiation

treatment.

CO187. Exposure to radiology

departments.

CO188. Examine various cell

types      by      blood              smear preparation

CO189.         Estimate                     the

biochemical parameters.

CO190. Design and

Calculate LD50/30

CO191. Demonstrate skills and record the concepts  in the form  of practical file  and

reflect  on  personal learning experiences and experimental outcomes during viva voce.

CO192. Contribute effectively

in course-specific interaction

Approach in

teaching:

Practical, Reading

assignments,

Demonstration

Learning

activities for the

students:

Practical

knowledge,

Effective questions

Class test

Semester

end

examinations

Viva voce

 

CONTENTS

Histopathological, Histochemical & Biochemical studies of various tissues after external & internal radiation
A visit to Radiology Deptt. SMS Medical College,Jaipur
Calculation of LD50/30 in mice after exposure to different radiation doses.
Histopathological studies of various organs after radiation treatment- liver,kidney,spleen,intestine and testis.
Biochemical estimation of:
DNA
RNA
Glucose
LPO
GSH
Study of various cell types by blood smear preparation

Exercise 1

Exercise II

File

Viva

Attendance

Total

5

5

10

5

5

30

Scheme for CA End Practical Examination

Sc

Exercise I

Exercise

II

Exercise

III

Exercise

IV

Spotting

File

Viva

Total

8

8

8

8

6x3=18

10

10

70

heme for M.Sc Semester End Practical Examination

Essential Readings: 
Ramesha Rao. : Who runs the risk of cancer.ShipraPublication.
Alberts. B. Bras D. lenis J. : Molecular Biology of the cells. Govland Publishing NewYork.
Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B.Lippincott.
 
SUGGESTED READINGS:
Hall. E. J. Radiobiology for the radio biologists. Lippincott. Philadelphia.
P.S. Lotran. V. Kumar. T.collins. : Pathology of DiseasesRobbins.
Peekham. M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of oncology Vol.I.. Vol. II. Oxford Medical Publication. Oxford University Press. Inc. New York1995.
Tannode. 1 F and Richand P. : The Basic science of oncology. ThII. MacGraw-Hill
Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology. Thomson press Ltd.. NOIDA. 1999.
Weiss. L. : Principles of metastases. Acdemic press.
 
Academic Year: