Cancer and Radiation Biology II

Paper Code: 
ZOL 423A
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Course objectives:

This course will enable the students to -

  1. Develop an understanding of types of cancer and their causes.
  2. Differentiate and evaluate the role of radiations in cancer and their treatment.

 

Course Outcomes (COs):

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 423A

 

Cancer And Radiation Biology II

Students will :–

CO131: Develop skills, concepts and experience to understand types of cancer and their causes

CO132: Describe various  roles of radiations in cancer and their treatment.

CO133: Develop an understanding of radiation safety and regulatory aspects.

CO134: Analyse and demonstrate types of cancer and their mechanisms radiation safety and regulatory aspects.

CO135: Differentiate and evaluate the role of radiations in cancer and their treatment.

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching

Learning activities for the students:

Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

Class test

Semester end examinations,

Quiz

Assignments,

Presentations

Surprise test

Open book test
 

 

12.00
Unit I: 
UNIT I

Causation of cancer:

  • Hereditary cancer.
  • Virus and cancer
  • Chemical carcinogenesis
  • Hormones and cancer
  • Nutrition and cancer
  • Radiation carcinogenesis: Basic concept of free radicals and their role in cancer

 

12.00
Unit II: 
UNIT II

Therapy of cancer.

Surgical removal.

  • Chemotherapy
  • Radiotherapy.
  • Immunotherapy.
  • Hyperthermia.
  • Management of therapy of cancer. Prevention of cancer.
  • Primary prevention: Education, motivation, legislation.
  • Secondary prevention.
  • Detection of precancerous and early cancerous lesions

Chemoprevention.

 

12.00
Unit III: 
UNIT III
Acute radiation effects.
● Concept of LD50.
● Central nervous system syndrome.
● Gastro-intestinalsyndrome.
● Bone. Marrow syndrome.
Skin reactions
 
12.00
Unit IV: 
UNIT IV
Delayed effects of Radiation.
● Stochastic and deterministic effects.
● Radiologicaging,
● Life shortening.
● Radiation carcinogenesis
 
12.00
Unit V: 
UNIT V

Radiation safety and regulator aspects.

  • Radiographic installations.
  • Enclosed installations.
  • Field installations.
  • Personnel management.
  • Source storage facilities.
  • Safe work practice.
  • Recommendations ofNational/international statutory bodies

 

Essential Readings: 
  • Ramesha Rao. : Who runs the risk of cancer.ShipraPublication.
  • Alberts. B. Bras D. lenis J. : Molecular Biology of the cells. Govland Publishing NewYork.
  • Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B.Lippincott.

 

References: 

SUGGESTED READINGS:

  • Hall. E. J. Radiobiology for the radio biologists. Lippincott. Philadelphia.
  • P.S. Lotran. V. Kumar. T.collins. : Pathology of DiseasesRobbins.
  • Peekham. M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of oncology Vol.I.. Vol. II. Oxford Medical Publication. Oxford University Press. Inc. New York1995.
  • Tannode. 1 F and Richand P. : The Basic science of oncology. ThII. MacGraw-Hill
  • Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology. Thomson press Ltd.. NOIDA. 1999.
  • Weiss. L. : Principles of metastases. Acdemic press.

 

Academic Year: 
2022-2023
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