Cancer and Radiation Biology II

Paper Code: 
ZOL 423A
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 
This course will enable the students to -
1. Develop an understanding of types of cancer and their causes.
2. Differentiate and evaluate the role of radiations in cancer and their treatment.
 
 

Course

Learning outcomes

(at course level)

Learning and teaching strategies

Assessment Strategies

Paper Code

Paper Title

ZOL 423A

 

Cancer And Radiation Biology II

Students will :–

CO131: Develop skills, concepts and experience to understand types of cancer and their causes

CO132:Describe various  roles of radiations in cancer and their treatment.

CO133: Develop an understanding of radiation safety and regulatory aspects.

CO134: Analyse and demonstrate  types of cancer and their mechanisms radiation safety and regulatory aspects.

CO135: Differentiate and evaluate the role of radiations in cancer and their treatment.

 

 

Approach in teaching:

Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching

Learning activities for the students:

Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Field practical

Class test

Semester end examinations,

Quiz

Assignments,

Presentations

Surprise test

Open book test
 

 

12.00
Unit I: 
UNIT I
Causation of cancer:
● Hereditary cancer.
● Virus and cancer
● Chemical carcinogenesis
● Hormones and cancer
● Nutrition and cancer
● Radiation carcinogenesis:Basic concept of free radicals and their role in cancer
12.00
Unit II: 
UNIT II
Therapy of cancer.
Surgical removal.
● Chemotherapy
● Radiotherapy.
● Immunotherapy.
● Hyperthermia.
● Management of therapy of cancer. Prevention of cancer.
● Primary prevention : Education, motivation, legislation.
● Secondary prevention.
● Detection of precancerous and early cancerous lesions
Chemoprevention.
.
 
12.00
Unit III: 
UNIT III
 
Acute radiation effects.
● Concept of LD50.
● Central nervous system syndrome.
● Gastro-intestinalsyndrome.
● Bone. Marrow syndrome.
Skin reactions
12.00
Unit IV: 
UNIT IV
 
 
Delayed effects of Radiation.
● Stochastic and deterministic effects.
● Radiologicaging,
● Life shortening.
● Radiation carcinogenesis.
 
12.00
Unit V: 
UNIT V
 
Radiation safety and regulator aspects.
 
● Radiographic installations.
● Enclosed installations.
● Field installations.
● Personnel management.
● Source storage facilities.
● Safe work practice.
● Recommendations ofNational/international statutory bodies
 
Essential Readings: 
● Ramesha Rao. : Who runs the risk of cancer.ShipraPublication.
● Alberts. B. Bras D. lenis J. : Molecular Biology of the cells. Govland Publishing NewYork.
● Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B.Lippincott.
● Hall. E. J. Radiobiology for the radio biologists. Lippincott.Philadelphia.
● P.S. Lotran. V. Kumar. T.collins. : Pathology of DiseasesRobbins.
● Peekham. M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of oncology Vol.I.. Vol. II. Oxford Medical Publication. Oxford University Press. Inc. New York1995.
● Tannode. 1 F and Richand P. : The Basic science of oncology. ThII. MacGraw-Hill
● Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology. Thomson press Ltd.. NOIDA. 1999.
● Weiss. L. : Principles of metastases. Acdemic press.
Academic Year: 
2021-2022
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