CANCER AND RADIATION BIOLOGY II

Paper Code: 
ZOL-423(A)
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 

Radiotherapy and Cancer Prevention

Objectives- The course Objectives to provide students with a detailed knowledge of:

  1. Types of cancer and their causes
  2. Role of radiations in cancer and their treatment.

 

12.00
Unit I: 
UNIT I

Causation of cancer :

  • Hereditary cancer.
  • Virus and cancer
  • Chemical carcinogenesis
  • Hormones and cancer
  • Nutrition and cancer
  • Radiation carcinogenesis:Basic concept of free radicals and their role in cancer
12.00
Unit II: 
UNIT II

Therapy of cancer.

  • Surgical removal.
  • Chemotherapy
  • Radiotherapy.
  • Immunotherapy.
  • Hyperthermia.
  • Management of therapy of cancer.

Prevention of cancer.

  • Primary prevention : Education, motivation, legislation.
  • Secondary prevention.
    • Detection of precancerous and early cancerous lesions
    • Chemoprevention.
12.00
Unit III: 
UNIT III

Acute radiation effects.

  • Concept of LD50.
  • Central nervous system syndrome.
  • Gastro-intestinal syndrome.
  • Bone.marrow syndrome.
  • Skin reactions.
12.00
Unit IV: 
UNIT IV

Delayed effects of Radiation.

  • Stochastic and deterministic effects.
  • Radiologic aging,
  • Life shortening.
  • Radiation carcinogenesis.

 

12.00
Unit V: 
UNIT V

Radiation safety and regulator aspects.

  • Radiographic installations.
  • Enclosed installations.
  •    Field installations.
  • Personnel management.
  • Source storage facilities.
  • Safe work practice.

  Re-commendations of National/international statutory bodies

Essential Readings: 
  • RameshaRao. : Who runs the risk of cancer. Shipra Publication.
  • Alberts.  B.  Bras  D.  lenis J.   :  Molecular Biology of the  cells.  Govland
    Publishing New York.
  • Devita VT. Cancer Prevention. Hellmos. Rosensey. S.A. J.B. Lippincott.
  • Hall. E. J. Radiobiology for the radiobiologists. Lippincott. Philadelphia.
  • P.S. Lotran. V. Kumar. T.collins. : Pathology of Diseases Robbins.
  • Peekham.   M.. Herbert M. Pinedo. Umberto Veronesi. : Oxford textbook of
    oncology Vol. I.. Vol.  II. Oxford Medical Publication. Oxford University
    Press. Inc. New York 1995.
  • Tannode.  1  F  and  Richand  P.   :  The  Basic  science  of oncology.  ThII.
    MacGraw-Hill
  • Vinay Kumar. Ramzi. S. Cotran and Stranley L. Robbins. : Basic pathology.
    Thomson press Ltd.. NOIDA. 1999.
  • Weiss. L. : Principles of metastases. Acdemic press.

 

Academic Year: 
2019-2020
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