BIOCHEMISTRY OF METABOLIC PROCESSES

Paper Code: 
25CZOL411
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 
This course will enable the students to -
1. Differentiate between the structure and function of biomolecules and their role in homeostasis.
2. Acquire knowledge and understanding about enzymes classification, kinetics and factors affecting enzyme activity.
 
Course Outcomes: 

Course

Learning outcomes (at course level)

Learning and teaching strategies

Assessmen t Strategies

Course Code

Course Title

 

 

 

 

 

 

 

 

 

 

25CZOL411

 

 

 

 

 

 

 

 

 

Biochemistry of Metabolic Processes

CO:73 Develop understanding about carbohydrates types, structure, properties and their metabolic pathways.

CO:74 Explore lipid structure and significance, including metabolic processes.

CO:75 Illustrate amino acids and protein structure, properties, classification and catabolic biochemical processes.

CO:76 Investigate nucleic acid structure, DNA/RNA types, and complementary base pairing.

CO:77 Study enzymes, including their classification, mechanism, kinetics, and regulation.

CO:78 Contribute effectively in course-specific interaction

The approach in teaching: Lectures, Discussion, Tutorials, Reading assignments,

Demonstratio n, Team teaching

Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Chart preparation

Assessmen t Strategies Continuous assessment, Semester end examination s,         Quiz, Solving problems in tutorials, Assignments

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Presentation.

 

12.00
Unit I: 
Carbohydrates
Structure, properties and biological importance:
Monosaccharides, Disaccharides, Polysaccharides and Glycoconjugates Metabolism- Glycolysis, Krebs cycle, Glycogenesis and glycogenolysis
 
12.00
Unit II: 
Lipids
Structure and Significance:
Physiologically important saturated and unsaturated fatty acids, Triacylglycerols, Phospholipids, glycolipids, Steroids
Beta oxidation of palmitic acid 
 
12.00
Unit III: 
Proteins
Amino acids: Structure, Classification and General properties of α-amino acids; Physiological importance of essential and non-essential α-amino acids Levels of organization in proteins;
Denaturation;
Introduction to simple and conjugated proteins Transamination, Deamination, Urea cycle, decarboxylation.
 
12.00
Unit IV: 
Nucleic Acids
Structure: Purines and pyrimidines, Nucleosides, Nucleotides,
Nucleic acids Cot Curves: Basepairing, Denaturation and Renaturation of DNA
Types of DNA and RNA, Complementarity of DNA,
 
12.00
Unit V: 
Enzymes
Nomenclature and classification;
Cofactors; Specificity of enzyme action; Isozymes; Mechanism of enzyme action; Enzyme kinetics; Factors affecting rate of enzyme-catalysed reactions;
Derivation of Michaelis-Menten equation, Concept of Km and Vmax,
 
Essential Readings: 
● U. Satyanaryana . Biochemistry IV Edition, Elsevier (2013)
● Jain ,J. L. Fundamentals of Biochemistry , S.Chand publishers New Delhi.
● Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.(2007)
● Lehninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors, Shahdara, Delhi.
● Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV Edition. W.H. Freeman and Co
 
SUGGESTED READINGS:
● Harvey, Richard A., Ph. D. (2011). Lippincott illustrated reviews: Biochemistry. Philadelphia :Wolters Kluwer Health
● Principles of Biochemistry; Smith et.al; McGraw Hill, New York.
● Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R;27 Orient Longman, Madras
● Donald Voet and Judith G. Voet Biochemistry, John Wiley and Sons., New York.
● H.S. Srivastava, Element of Biochemistry, Rastogi Publications Meerut.
 
References: 
e-RESOURCES:
● 2014 Kaplan lecture video series on Biochemistry by Dr. Turco https://afratafreeh.com/sam-turco/
● e-PGPATHSHALA-INFLIBNET CENTRE-
● Biochemistry- Swayam Prabha-https://dth.ac.in/medical/course.php
 
e-JOURNAL:
● Journal of Biochemistry- ISSN 1756-2651
● Biochemistry- ACS Publication- ISSN 1520-4995
● Journal of Cellular Biochemistry- Wiley online Library- Online ISSN: 1097-4644 
 
Academic Year: 
2025-2026
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