BIOCHEMISTRY OF METABOLIC PROCESSES

Paper Code: 
24CZOL411
Credits: 
4
Contact Hours: 
60.00
Max. Marks: 
100.00
Objective: 
Course objectives: 
This course will enable the students to - 
1. Differentiate between the structure and function of biomolecules and their role in homeostasis.
2. Acquire knowledge and understanding about enzymes classification, kinetics and factors affecting enzyme activity.
 
Course Outcomes: 

Course

Learning outcomes

(at course level)

Learning and 

teaching strategies

Assessment

Strategies

 Course Code

Course Title

24CZOL 411

Biochemistry of  Metabolic 

Processes

CO:73 Develop understanding about carbohydrates types, structure, properties and their metabolic pathways.

CO:74 Explore lipid structure and significance, including metabolic processes.

CO:75 Illustrate amino acids  and protein structure, properties, classification and catabolic biochemical processes.

CO:76 Investigate nucleic acid structure, DNA/RNA types, and complementary base pairing.

CO:77 Study enzymes, including their classification, mechanism, kinetics, and regulation.

CO:78 Contribute effectively in course-specific interaction

The approach in  teaching:

Lectures, 

Discussion, Tutorials, Reading  assignments, 

Demonstration,  Team teaching

 

Learning activities for the students: Self-learning 

assignments, Effective 

questions, Simulation, 

Seminar presentation, 

Giving tasks,  Chart preparation

Assessment 

Strategies

Continuous assessment, Semester  end examinations,  Quiz, Solving  problems in tutorials,  Assignments, 

Presentation.

 

12.00
Unit I: 
Carbohydrates
Structure, properties and biological importance: 
Monosaccharides, Disaccharides, Polysaccharides and Glycoconjugates 
Metabolism- Glycolysis, Krebs cycle, Glycogenesis and glycogenolysis  
 
12.00
Unit II: 
Lipids

Structure and Significance: 

Physiologically important saturated and unsaturated fatty acids, 
Triacylglycerols, Phospholipids, glycolipids, Steroids 
Beta oxidation of palmitic acid,
12.00
Unit III: 
Proteins
Amino acids: Structure, Classification and General properties of α-amino acids; Physiological importance of essential and non-essential α-amino acids Levels of organization in proteins; 
Denaturation; 
Introduction to simple and conjugated proteins 
Transamination, Deamination, Urea cycle, decarboxylation
 
12.00
Unit IV: 
Nucleic Acids
Structure: Purines and pyrimidines, 
Nucleosides, Nucleotides, Nucleic acids 
Cot Curves: Base pairing, 
Denaturation and Renaturation of DNA 
Types of DNA and RNA, Complementarity of DNA
 
12.00
Unit V: 
Enzymes
Nomenclature and classification; 
Cofactors; Specificity of enzyme action; Isozymes; 
Mechanism of enzyme action; Enzyme kinetics; 
Factors affecting rate of enzyme-catalysed reactions; 
Derivation of Michaelis-Menten equation, Concept of Km and Vmax,  
 
Essential Readings: 
ESSENTIAL READINGS: 
● U. Satyanaryana . Biochemistry IV Edition, Elsevier (2013) 
● Jain ,J. L. Fundamentals of Biochemistry , S.Chand publishers New Delhi. 
● Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.(2007) 
● Lehninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors,  Shahdara, Delhi. 
● Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV  Edition. W.H. Freeman and Co 
 
SUGGESTED READINGS: 
● Harvey, Richard A., Ph. D. (2011). Lippincott illustrated reviews: Biochemistry.  Philadelphia :Wolters Kluwer Health 
● Principles of Biochemistry; Smith et.al; McGraw Hill, New York. 
● Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R;27  Orient Longman, Madras 
● Donald Voet and Judith G. Voet Biochemistry, John Wiley and Sons., New York. 
● H.S. Srivastava, Element of Biochemistry, Rastogi Publications Meerut. 
 
e-RESOURCES:
● 2014 Kaplan lecture video series on Biochemistry by Dr. Turco 
● e-PGPATHSHALA-INFLIBNET CENTRE- 
● Biochemistry- Swayam Prabha-https://dth.ac.in/medical/course.php 
 
e-JOURNAL: 
● Journal of Biochemistry- ISSN 1756-2651 
● Biochemistry- ACS Publication- ISSN 1520-4995 
● Journal of Cellular Biochemistry- Wiley online Library- Online ISSN: 1097-4644
 
Academic Year: 
2024-2025
  • Printer-friendly version
  • PDF version