Biochemistry II

Paper Code: 
ZOL -211
Credits: 
3
Contact Hours: 
45.00
Max. Marks: 
100.00
Objective: 
Course objectives:  
This course will enable the students to – 
1. Appraise structural elements of proteins, its configuration, classification and details of protein  denaturation and its utility in daily life.  
2. Critique the detailed catabolic and anabolic pathways of protein and nucleic acid metabolism. 
3. Examine bioenergetics and the law of Thermodynamics involved in biological processes. 
4. Analyze various kinds of minerals, their availability, transportation, metabolism and deficiency disorders. 
 
Course Outcomes (COs):  

Course 

Learning outcomes 

(at course level)

Learning and  teaching strategies

Assessment  Strategies 

Paper  

Code

Paper Title

ZOL 211 

Biochemistry-II 

The students will : 

CO 24: Illustrate the information  regarding the structural elements  of proteins, its configuration,  classification and details of protein  denaturation and its utility in daily  life.  

CO 25: Appraise the detailed  catabolic and anabolic pathways of protein and nucleic acid  metabolism. 

CO 26: Relate Bioenergetics and  the law of Thermodynamics  involved in biological processes. CO 27: Develop in-depth  knowledge about various kinds of  minerals, their availability,  transportation, metabolism and  deficiency disorders.

The approach in  teaching: 

Interactive Lectures,  Discussion, Tutorials,  Reading assignments,  Demonstration, Team  teaching 

Learning activities for  the students: 

Self-learning  

assignments, Effective  questions, Simulation,  Seminar presentation,  Giving tasks, Chart  preparation

Assessment  Strategies 

Class test,  Semester end  examinations,  Quiz, Solving  problems in  tutorials,  

Assignments,  Presentation. 

 

9.00
Unit I: 
UNIT I: Proteins
● Classification & structural properties 
● Amino acids & peptides- Properties & structure 
● Configuration:Primary,Secondary,Tertiary,Quaternary 
● Ramachandran Plot
● Protein denaturation 
7.00
Unit II: 
UNIT II: Protein Metabolism and Diseases
● Catabolism of amino acids – Transamination, Transdeamination, Oxidative Deamination and  non oxidative deamination, Decarboxylation, Synthesis of Urea(Ornithine cycle) 
● Inborn errors of Protein metabolism (Alkaptonuria, Phenylketonuria, Maple Syrup,  Tyrosinemia, Albinism Urea Disorders) 
10.00
Unit III: 
UNIT III: Nucleic Acid
● Nucleic Acid and Nucleotides 
● Structural Properties and Functions 
● Nucleic Acid: Catabolism, Biosynthesis 
10.00
Unit IV: 
UNIT IV: Bioenergetics
● First and Second law of Thermodynamics 
● Standard free energy change 
● High energy phosphate compounds (ATP, GTP, Creatinine phosphate) 
9.00
Unit V: 
UNIT V: Mineral Metabolism
● Mineral Metabolism: (Source, Daily intake, Transportation, Absorption Functions, Deficiency and Diseases) 
● Iodine, 
● Zinc 
● Iron 
● Calcium, 
● Transport and Metabolism 
Essential Readings: 
• U. Satyanaryana . Biochemistry IV Edition, Elsevier (2013) 
• Jain,J.L.Fundamentals of Biochemistry ,S.Chand publishers New Delhi.
• Medical Physiology; Chatterjee, M.N and Shinde, R.; Jaypee brothers.(2007)
• Berg, J. M., Tymoczko, J. L. and Stryer, L.  Biochemistry. VI Edition. W.H Freeman  and Co. 
• Lehninger, A.D. Principles of Biochemistry, CBS Publishers and Distributors, Shahdara, Delhi. 
• Nelson, D. L., Cox, M. M. and Lehninger, A.L. (2009). Principles of Biochemistry. IV Edition.  W.H. Freeman and Co
References: 
SUGGESTED READINGS:
• Harvey, Richard A., Ph. D. (2011). Lippincott's illustrated reviews: Biochemistry. Philadelphia :Wolters Kluwer Health
• Tortora, G.J. and Derrickson, B.H. (2009). Principles of Anatomy and Physiology, XII Edition,  John Wiley & Sons, Inc. 
• Principles of Biochemistry; Smith et.al; McGraw Hill, New York. 
• Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R; Orient  Longman, Madras 
• Conn, E.E. and Stuff, P.K. Outlines of Biochemistry,John Wiley New York. 
• Donald Voet and Judith G. Voet Biochemistry, John Wiley and Sons., New York.  
• H.S. Srivastava, Element of Biochemistry, Rastogi Publications Meerut.  
 
e-RESOURCES: 
• 2014 Kaplan lecture video series on Biochemistry by Dr. Turco-https://afratafreeh.com/sam-turco/
• e-PGPATHSHALA-INFLIBNET CENTRE-
• Biochemistry- Swayam Prabha-https://dth.ac.in/medical/course.php
 
e-JOURNAL:
• Journal of Biochemistry- ISSN 1756-2651
• Biochemistry- ACS Publication- ISSN 1520-4995
• Journal of Cellular Biochemistry- Wiley online Library- Online ISSN: 1097-4644
Academic Year: 
2022-2023
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