Coming soon
Biochemistry II
Course objectives:
This course will enable the students to –
- Appraise structural elements of proteins, its configuration, classification and details of protein denaturation and its utility in daily life.
- Critique the detailed catabolic and anabolic pathways of protein and nucleic acid metabolism.
- Examine bioenergetics and the law of Thermodynamics involved in biological processes.
- Analyze various kinds of minerals, their availability, transportation, metabolism and deficiency disorders.
Course Outcomes (COs):
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Course |
Learning outcomes (at course level) |
Learning and teaching strategies |
Assessment Strategies |
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Paper Code |
Paper Title |
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ZOL 211 |
Biochemistry-II |
The students will : CO 24: Illustrate the information regarding the structural elements of proteins, its configuration, classification and details of protein denaturation and its utility in daily life. CO 25: Appraise the detailed catabolic and anabolic pathways of protein and nucleic acid metabolism. CO 26: Relate Bioenergetics and the law of Thermodynamics involved in biological processes. CO 27: Develop in-depth knowledge about various kinds of minerals, their availability, transportation, metabolism and deficiency disorders. |
The approach in teaching: Interactive Lectures, Discussion, Tutorials, Reading assignments, Demonstration, Team teaching
Learning activities for the students: Self-learning assignments, Effective questions, Simulation, Seminar presentation, Giving tasks, Chart preparation |
Assessment Strategies Class test, Semester end examinations, Quiz, Solving problems in tutorials, Assignments, Presentation.
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Proteins
- Classification & structural properties
- Amino acids & peptides- Properties & structure
- Configuration:Primary,Secondary,Tertiary,Quaternary
- Ramachandran Plot, Protein Sequencing
- Protein denaturation
Protein Metabolism and Diseases
- Catabolism of amino acids – Transamination, Transdeamination, Oxidative Deamination and non oxidative deamination, Decarboxylation, Synthesis of Urea(Ornithine cycle)
- Inborn errors of Protein metabolism (Alkaptonuria, Phenylketonuria, Maple Syrup, Tyrosinemia, Albinism Urea Disorders)
Nucleic Acid
- Nucleic Acid And Nucleotides
- Structural Properties and Functions
- Nucleic Acid: Catabolism, Biosynthesis
Bioenergetics
- First and Second law of Thermodynamics
- Standard free energy change
- High energy phosphate compounds (ATP, GTP, Creatinine phosphate)
Mineral Metabolism
- Mineral Metabolism: (Source, Daily intake, Transportation, Absorption Functions, Deficiency and Diseases)
- Iodine,
- Zinc
- Iron
- Calcium,
- Transport and Metabolism
● Biochemistry; Stryer, L; Freeman Publications.
● Textbook of Medical Biochemistry; Ramakrishnan, S. Prasanan, K.G and Rajan, R.: Orient Longman, Madras
● Outlines of Biochemistry; Conn, E.E. and Stumpf P.K. ; John Wiley, New York.
● Principles of Biochemistry; Smith; McGraw hill, New York.
● Biochemistry, D.Voet and J.G.Voet, John Wiley & Sons, (2nd Edition), 1995.
● Principles of Biochemistry, Lehninger , Nelson and Cox, (3rd Edition), 1999.
● Principles and Techniques in Biochemistry and Molecular Biology, Edited by Keith Wilson and John Walker, Cambridge University Press, (6th Edition), 2007.
● Biochemistry and Molecular Biology by W.H. Elliot and Daphne C. Elliot, Oxford University Press, (3rd Edition), 2005.
● Biochemistry, J. David Rawn, Panima Publishing Corporation, 1st Indian Reprint, 2004.
● Physical Biochemistry, D Friefelder, W.H. Freeman & Company, 17th Reprint, 1999.
● Understanding Chemistry, CNR Rao, University Press, Hyderabad 1999.
● A Biologist's Guide to Principles and Techniques of Practical Biochemistry, K.Wilson& KH Goulding, ELBS Edition 1986.
Essentials of Molecular Biology, David Friefelder, Jones and Barllett Publications,7th Reprint, 2001.
